DRSC/TRiP Functional Genomics Resources

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Protein Alignment Utx and Tmtc3

DIOPT Version :9

Sequence 1:NP_609368.3 Gene:Utx / 34377 FlyBaseID:FBgn0260749 Length:1136 Species:Drosophila melanogaster
Sequence 2:XP_017450330.2 Gene:Tmtc3 / 314785 RGDID:1306351 Length:1022 Species:Rattus norvegicus


Alignment Length:543 Identity:118/543 - (21%)
Similarity:203/543 - (37%) Gaps:141/543 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   129 EYSEALSAYQKYLRFRENN--YWTNHAFIYGIGVAYFKLRCFKWAIKSFQELLYLSPNFTCANEV 191
            ||:..:||    |:..:||  .|.|      :|.|....:.|:.|:|.|.:..::.|:...|   
  Rat   538 EYTLFMSA----LKVNKNNAKLWNN------VGHALENEKNFEKALKYFLQATHVQPDDIGA--- 589

  Fly   192 HLRLGLMLKHCGEFHIALKHLQLALLYTYPSTFSELQVKFQIAHLYEVQNKHKAAKDGYEFLLNE 256
            |:.:|...|:......|.:...||     .|...::           :..|..||:    ...|.
  Rat   590 HMNVGRTYKNLNRTKEAEESYMLA-----KSLMPQI-----------IPGKKYAAR----IAPNH 634

  Fly   257 KNISLELKADVYRQLGWMYHCVECLGEKKEREANALNFLQKSIEADPKSGQSLYLLGRCYAGINK 321
            .|:.:.| |::.|           ..|.:..||:.|  .:::|...|...|:....|.....:||
  Rat   635 LNVYINL-ANLIR-----------ANESRLEEADQL--YRQAISMRPDFKQAYISRGELLLKMNK 685

  Fly   322 VHDAFLAYRNSVEKSEGNADTWCSIGVLYQQQNQPTDALQAYICAVQLDKDHKAAWTNLGILYES 386
            ...|..||..::|....|||.|.::.::|.:..:|.:||:.:..|::|:..||.|..|..||.:.
  Rat   686 PLKAKEAYLKALELDRNNADLWYNLAIVYIELKEPDEALKNFNRALELNSRHKLALFNSAILMQE 750

  Fly   387 CGQL------RDAYACYLNATKQIS---FQKSSLIRKKQAIRMKKDT---IGLSKGLSQRITFLE 439
            .|::      |.....|:|...|.:   |....|     |:..|||:   ..:.:.:..:..|..
  Rat   751 SGEVKLRPEARKRLLNYINEEPQDANGYFNLGML-----AMDDKKDSEAETWMKRAIKLQPDFRS 810

  Fly   440 GQLSQAPLPSITSKR-RQLCSIEEAWN----------LPISLEMNSRQ---------QQTAQMLP 484
            ...:.|.|.|.|:|. :.|..:||...          |...:.||.::         ::..:|.|
  Rat   811 ALFNLALLYSQTAKELKALPILEELLRYYPDHTKGLILKGDILMNQKKDIAGAKKCFEKILEMDP 875

  Fly   485 RQVTKQSPVQG----------------------------PPPPYPHSQLSQSPIPSKRIKEDGTS 521
                  |.|||                            |...|....||   |...:|...|..
  Rat   876 ------SNVQGKHNLCVVYFEEKDLLKAERCLVETLALAPHEEYIQRHLS---IVRDKIASSGIV 931

  Fly   522 QQEV--------TQNNSQTSAQNLIN-ISES----LNQRNFNAMPESNKSSEQSVLDTFDDISND 573
            .|.:        |:...:..::::.. ||||    :.:.|.|...:|||   ||..:...|..:.
  Rat   932 DQPLSPVDKTSGTEEKDEVPSEDVKEIISESRPAQIIKTNDNRKSQSNK---QSTGNADQDAPHK 993

  Fly   574 IYKQNESIKLERLSQDALSNNED 596
            ..|..:.|:.:|::  ||...|:
  Rat   994 TTKDIKEIEKKRVA--ALKRLEE 1014

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UtxNP_609368.3 TPR repeat 147..181 CDD:276809 9/35 (26%)
TPR_11 156..216 CDD:290150 13/59 (22%)
TPR repeat 186..216 CDD:276809 6/29 (21%)
TPR repeat 228..255 CDD:276809 3/26 (12%)
TPR_11 264..337 CDD:290150 16/72 (22%)
TPR repeat 265..300 CDD:276809 6/34 (18%)
TPR repeat 307..334 CDD:276809 7/26 (27%)
TPR_11 339..402 CDD:290150 20/68 (29%)
TPR repeat 339..369 CDD:276809 9/29 (31%)
TPR_1 340..373 CDD:278916 9/32 (28%)
TPR repeat 374..402 CDD:276809 9/33 (27%)
JmjC 870..978 CDD:202224
Tmtc3XP_017450330.2 DUF1736 366..438 CDD:400627
PEP_TPR_lipo <542..909 CDD:274350 89/424 (21%)
TPR repeat 553..581 CDD:276809 8/33 (24%)
TPR repeat 586..630 CDD:276809 11/66 (17%)
TPR repeat 637..664 CDD:276809 7/40 (18%)
TPR repeat 669..699 CDD:276809 7/29 (24%)
TPR repeat 704..732 CDD:276809 8/27 (30%)
TPR repeat 775..803 CDD:276809 6/32 (19%)
TPR repeat 808..838 CDD:276809 9/29 (31%)
TPR repeat 843..872 CDD:276809 3/28 (11%)
TPR repeat 878..901 CDD:276809 3/22 (14%)
ParB_N_Srx 901..>943 CDD:421688 8/44 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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