DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Utx and Lonrf3

DIOPT Version :9

Sequence 1:NP_609368.3 Gene:Utx / 34377 FlyBaseID:FBgn0260749 Length:1136 Species:Drosophila melanogaster
Sequence 2:XP_006257509.1 Gene:Lonrf3 / 298322 RGDID:1565451 Length:809 Species:Rattus norvegicus


Alignment Length:427 Identity:91/427 - (21%)
Similarity:149/427 - (34%) Gaps:132/427 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   311 LLGRCYAGINKVHDAFLAYRNSVEKSEGNADTWCSIGVLYQQQNQPTDALQAYICAVQLDKDHKA 375
            |||:.:.|         ..|.|..:.|||.        ||::: |...||..|..||:|..:...
  Rat   237 LLGKLFPG---------PARASQLRHEGNR--------LYRER-QVEAALLKYNEAVRLAPNDHL 283

  Fly   376 AWTNLGILYESCGQLRDA-----YACYLNATKQISFQKSSLIRKKQAIRMKKDTIGLSKGLSQRI 435
            .::|...:|.:.....||     .||.|   :.:.|:  :..||.||:.    |:|..|...:..
  Rat   284 LYSNRSQIYFTLESHEDALHDAEIACKL---RPMGFK--AHFRKAQALA----TLGKVKEALREF 339

  Fly   436 TFLEGQLSQAPLPSITSKRRQLCSIEEAWNLPISLE-MNSRQQQTAQMLPRQVTKQSPVQGPPPP 499
            .:                    |         :||: .|.|.:..||.|......        |.
  Rat   340 LY--------------------C---------VSLDGKNKRARSEAQRLLFSFFS--------PS 367

  Fly   500 YPHSQLSQSP------IPSKRIKE-------DGTSQQ--EVTQNNSQ-------------TSAQN 536
            .|......||      .|..|:||       :|||..  :::|.||:             ..:.:
  Rat   368 VPGESQEHSPDILKLLAPHPRLKEHVESMATEGTSHNLPKLSQENSELPHCSNQEGAAAREESSS 432

  Fly   537 LINISESLNQRNFNAMPESNKSSEQSVLDTFD-DISNDIYKQNESIKLERLSQDALSNNEDSRHD 600
            |:|:::....|.    .:..||.|:...|... .....:.|:....::| ..:|....|:.|:.|
  Rat   433 LVNMAQGKVSRK----EDRAKSQEEEEQDAASVRTGKCLEKKRNRCQIE-TQEDTELPNKVSKQD 492

  Fly   601 FIG--GDNADISTTFKIQMDSKQL--MVAVKLL--PIDEPPVHCTILQV-------NAPPPSPPD 652
            ...  |...|:|.... ..|:..|  .:.::|.  |:..|..|...|:.       ||      .
  Rat   493 LPAEQGAKPDLSIPLG-SFDASDLECSLCMRLFYEPVTTPCGHTFCLKCLERCLDHNA------K 550

  Fly   653 CPPQKLTRDQLLPPTPSVHLENKKHAFSPQLQEFCLK 689
            ||   |.:|.||...||     :|::.:..::|...|
  Rat   551 CP---LCKDVLLQCLPS-----RKYSKNVIMEELIAK 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UtxNP_609368.3 TPR repeat 147..181 CDD:276809
TPR_11 156..216 CDD:290150
TPR repeat 186..216 CDD:276809
TPR repeat 228..255 CDD:276809
TPR_11 264..337 CDD:290150 6/25 (24%)
TPR repeat 265..300 CDD:276809
TPR repeat 307..334 CDD:276809 6/22 (27%)
TPR_11 339..402 CDD:290150 17/67 (25%)
TPR repeat 339..369 CDD:276809 9/29 (31%)
TPR_1 340..373 CDD:278916 9/32 (28%)
TPR repeat 374..402 CDD:276809 7/32 (22%)
JmjC 870..978 CDD:202224
Lonrf3XP_006257509.1 RING 163..200 CDD:302633
TPR_11 247..313 CDD:290150 21/77 (27%)
TPR repeat 248..276 CDD:276809 11/36 (31%)
TPR repeat 281..311 CDD:276809 6/29 (21%)
TPR repeat 316..339 CDD:276809 8/28 (29%)
RING 516..555 CDD:238093 10/47 (21%)
LON_substr_bdg 605..806 CDD:280370
LON 616..802 CDD:271862
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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