DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Utx and ttc32

DIOPT Version :9

Sequence 1:	NP_609368.3	Gene:	Utx / 34377	FlyBaseID:	FBgn0260749	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	NP_001020691.1	Gene:	ttc32 / 100004012	ZFINID:	ZDB-GENE-041014-158	Length:	136	Species:	Danio rerio

Alignment Length:	165	Identity:	38/165 - (23%)
Similarity:	61/165 - (36%)	Gaps:	50/165 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KNAELRNLVQQTITNLQNYIANGQVHESKNSSDNKNAIQKFEPSTQAGEHMENTSSRNNDDTKPF 93
            :|:||:.|              .:.||..||.:.|.|.:.:   ||..|....:...|..|
Zfish     2 ENSELKIL--------------QKAHEEFNSKNYKRAEELY---TQFIESCTKSRDCNGQD---- 45

  Fly    94 EQDAKEKVSIIEEKHQDEHYVNALCKLGHLHLLLGEYSEALSAYQKYLRFRENNYWTNHAF---I 155
                   ::|.        |.|.    |.:..|..::.||:..|...:..       |..|   :
Zfish    46 -------LAIA--------YNNR----GQVKYLRVDFYEAMDDYTSAIHI-------NRQFEVPL 84

  Fly   156 YGIGVAYFKLRCFKWAIKSFQELLYLSPNFTCANE 190
            |..|:..::|..||.|...|:.:|.|:|:|..|.|
Zfish    85 YNRGLIRYRLGFFKEAEGDFRRVLELNPDFKDAKE 119

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Utx	NP_609368.3	TPR repeat	147..181	CDD:276809	10/36 (28%)
		TPR_11	156..216	CDD:290150	13/35 (37%)
		TPR repeat	186..216	CDD:276809	2/5 (40%)
		TPR repeat	228..255	CDD:276809
		TPR_11	264..337	CDD:290150
		TPR repeat	265..300	CDD:276809
		TPR repeat	307..334	CDD:276809
		TPR_11	339..402	CDD:290150
		TPR repeat	339..369	CDD:276809
		TPR_1	340..373	CDD:278916
		TPR repeat	374..402	CDD:276809
		JmjC	870..978	CDD:202224
ttc32	NP_001020691.1	TPR_11	9..77	CDD:290150	20/114 (18%)
		TPR repeat	9..33	CDD:276809	9/40 (23%)
		TPR repeat	46..76	CDD:276809	8/41 (20%)
		TPR_11	47..112	CDD:290150	19/83 (23%)
		TPR repeat	81..109	CDD:276809	7/27 (26%)
		TPR_1	84..114	CDD:278916	10/29 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900