DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4953 and TRAPPC13

DIOPT Version :10

Sequence 1:NP_609365.3 Gene:CG4953 / 34373 FlyBaseID:FBgn0032204 Length:438 Species:Drosophila melanogaster
Sequence 2:NP_001087224.1 Gene:TRAPPC13 / 80006 HGNCID:25828 Length:418 Species:Homo sapiens


Alignment Length:417 Identity:192/417 - (46%)
Similarity:257/417 - (61%) Gaps:17/417 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEMVEP-DAHLVALKVMRLMRPTLVGLGPVVTCEPTDLV-QRFSSSQESDGMSGACAETLAAGQV 63
            ||:..| ..||:|||||||.:|||....| ||||..||. ..|:.....|..:...||.|..|::
Human     1 MEVNPPKQEHLLALKVMRLTKPTLFTNIP-VTCEEKDLPGDLFNQLMRDDPSTVNGAEVLMLGEM 64

  Fly    64 LLLPQSFGSIYLGETFASYICVHNTTPNPVECVTVKADLQSNTSRINLSMHENAKSPVVLPPGGT 128
            |.|||:||:|:|||||:|||.|||.:...|:.:.||||||:::.|:|||....|.:.  |.|...
Human    65 LTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAE--LKPDCC 127

  Fly   129 IDDVIRYEVKEIGTHILVCEVNYSTPAGYAQSLRKFFKFQVLKPLDVKTKFYNAE------IDEI 187
            |||||.:||||||||||||.|:|:|.||.....||||||||||||||||||||||      .||:
Human   128 IDDVIHHEVKEIGTHILVCAVSYTTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEV 192

  Fly   188 YLEAQIQNVTTSPFCLEKVELDGSEDYSVTPLNTLPN-GE--SVFTVKHMLQPNNSCQFLYCIKP 249
            :|||||||:||||..:|||.|:.|..|:||.||::.. ||  |.|..:..|||.::.|:|||:||
Human   193 FLEAQIQNMTTSPMFMEKVSLEPSIMYNVTELNSVSQAGECVSTFGSRAYLQPMDTRQYLYCLKP 257

  Fly   250 KGDIAKNVDTLRQFNNVGKLDIVWRSNLGEKGRLQTSQLQRLPFECKTLRLEVLDAKNTIKIGTI 314
            |.:.|:....::....:|||||||::||||:||||||||||:......:||.:....:|:.:...
Human   258 KNEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEP 322

  Fly   315 FTFNCRVTN-TSEHPMKLNVRLAAKFSPDSQYTGCADFMLNLLQSGESAEFPLSVCPSKLGLVKI 378
            |...|::|| :||..|.|.:.:....|  ..:.|.:...|..|....|....|::..|..||..|
Human   323 FHITCKITNCSSERTMDLVLEMCNTNS--IHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSI 385

  Fly   379 TPLVLTNTLQNEQFTIENVVDVFVVNS 405
            :.|.||:|.....:..:::..|.||:|
Human   386 SGLRLTDTFLKRTYEYDDIAQVCVVSS 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4953NP_609365.3 DUF974 64..290 CDD:461841 133/234 (57%)
TRAPPC13NP_001087224.1 DUF974 65..298 CDD:461841 133/234 (57%)

Return to query results.
Submit another query.