DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment REPTOR-BP and crebl2

DIOPT Version :9

Sequence 1:	NP_609363.1	Gene:	REPTOR-BP / 34371	FlyBaseID:	FBgn0032202	Length:	118	Species:	Drosophila melanogaster
Sequence 2:	NP_001002702.2	Gene:	crebl2 / 436975	ZFINID:	ZDB-GENE-040718-456	Length:	119	Species:	Danio rerio

Alignment Length:	109	Identity:	55/109 - (50%)
Similarity:	69/109 - (63%)	Gaps:	17/109 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADMEIQSNKMSITEETQVQTRKECGKRGRKPGRKTSTEKLDMKAKLERSRQSARECRARKKLRY 65
            |.|.:|.:.|:           |:.|||||||.      |:|:||||||||||||||||||||||
Zfish     1 MDDSKIVAGKV-----------KKPGKRGRKPA------KIDLKAKLERSRQSARECRARKKLRY 48

  Fly    66 QYLEELVADREKAVVALRTELERLIQWNNQLSESNTPTNNDQLL 109
            |||||||:.:|:|:.|||.||:...||...:.:...|:....||
Zfish    49 QYLEELVSSKERAICALREELDMYKQWCLAMDQGKIPSEIKALL 92

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
REPTOR-BP	NP_609363.1	bZIP_CREBL2	42..97	CDD:269857	39/54 (72%)
REPTOR-BP	NP_609363.1	coiled coil	43..94	CDD:269857	38/50 (76%)
crebl2	NP_001002702.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23		12/38 (32%)
		bZIP_CREBL2	25..80	CDD:269857	39/54 (72%)
		coiled coil	26..77	CDD:269857	38/50 (76%)
		Basic motif. /evidence=ECO:0000250	29..60		27/30 (90%)
		Leucine-zipper. /evidence=ECO:0000250	62..69		3/6 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..119
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589292
Domainoid	1	1.000	73	1.000	Domainoid score	I9219
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1003
Inparanoid	1	1.050	97	1.000	Inparanoid score	I5031
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551209at2759
OrthoFinder	1	1.000	-	-		FOG0007856
OrthoInspector	1	1.000	-	-		oto39896
orthoMCL	1	0.900	-	-		OOG6_108534
Panther	1	1.100	-	-	LDO	PTHR21051
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5183
SonicParanoid	1	1.000	-	-		X5809
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.930