DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment REPTOR-BP and crebl2

DIOPT Version :9

Sequence 1:	NP_609363.1	Gene:	REPTOR-BP / 34371	FlyBaseID:	FBgn0032202	Length:	118	Species:	Drosophila melanogaster
Sequence 2:	NP_001090852.1	Gene:	crebl2 / 100038265	XenbaseID:	XB-GENE-940117	Length:	118	Species:	Xenopus tropicalis

Alignment Length:	109	Identity:	56/109 - (51%)
Similarity:	68/109 - (62%)	Gaps:	17/109 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADMEIQSNKMSITEETQVQTRKECGKRGRKPGRKTSTEKLDMKAKLERSRQSARECRARKKLRY 65
            |.|.::...|:           |:.|||||||.      |:|:||||||||||||||||||||||
Frog     1 MDDSKVSGGKV-----------KKPGKRGRKPA------KIDLKAKLERSRQSARECRARKKLRY 48

  Fly    66 QYLEELVADREKAVVALRTELERLIQWNNQLSESNTPTNNDQLL 109
            |||||||:.||:|:.|||.|||...||...:.:...|:....||
Frog    49 QYLEELVSSRERAICALREELEMYKQWCAAMDQGKIPSEIKALL 92

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
REPTOR-BP	NP_609363.1	bZIP_CREBL2	42..97	CDD:269857	41/54 (76%)
REPTOR-BP	NP_609363.1	coiled coil	43..94	CDD:269857	40/50 (80%)
crebl2	NP_001090852.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25		12/40 (30%)
		bZIP_CREBL2	25..80	CDD:269857	41/54 (76%)
		coiled coil	26..77	CDD:269857	40/50 (80%)
		Basic motif. /evidence=ECO:0000250	29..60		28/30 (93%)
		Leucine-zipper. /evidence=ECO:0000250	62..69		3/6 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I8940
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1003
Inparanoid	1	1.050	100	1.000	Inparanoid score	I4866
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1551209at2759
OrthoFinder	1	1.000	-	-		FOG0007856
OrthoInspector	1	1.000	-	-		oto103617
Panther	1	1.100	-	-	LDO	PTHR21051
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5183
SonicParanoid	1	1.000	-	-		X5809
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100