DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rsf1 and Srsf3

DIOPT Version :9

Sequence 1:	NP_001260318.1	Gene:	Rsf1 / 34370	FlyBaseID:	FBgn0011305	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_038691.1	Gene:	Srsf3 / 20383	MGIID:	98285	Length:	164	Species:	Mus musculus

Alignment Length:	185	Identity:	73/185 - (39%)
Similarity:	89/185 - (48%)	Gaps:	37/185 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RVYVGNLTDKVKKDDLEGEFTKYGKLNSVWIAFNPPGFAFVEFEHRDDAEKACDILNGSELLGSQ 75
            :||||||.:...|.:||..|..||.|.|||:|.|||||||||||...||..|...|:|..|.|.:
Mouse    11 KVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRTLCGCR 75

  Fly    76 LRVEISKGRPRQGRRGGPMDRGGR-RGDFGRHSITSGGSGGGGFRQRGSSGSSSRHTERGYSSGR 139
            :|||:|.|..|...||.|...|.| |.|:.|.|...        |:|     |.|  .|.:|..|
Mouse    76 VRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPP--------RRR-----SPR--RRSFSRSR 125

  Fly   140 SGASSYNGREGGGSGFNRREVYGGGRDSSRYSSGS-SASYGRTGGQSAGRFRSRS 193
            |.:.|.:         .|||     |..||..:.. |.|:.|:      |.||||
Mouse   126 SRSLSRD---------RRRE-----RSLSRERNHKPSRSFSRS------RSRSRS 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rsf1	NP_001260318.1	RRM_SRSF3_like	11..82	CDD:409808	38/70 (54%)
Srsf3	NP_038691.1	Sufficient for interaction with NXF1. /evidence=ECO:0000250	1..90		41/78 (53%)
		RRM_SRSF3	6..86	CDD:241089	40/74 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..164		35/115 (30%)
		2 X approximate repeats, basic	119..164		19/62 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0107
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1533297at2759
OrthoFinder	1	1.000	-	-		FOG0000474
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920