DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ror and AT5G65600

DIOPT Version :9

Sequence 1:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_201363.1	Gene:	AT5G65600 / 836686	AraportID:	AT5G65600	Length:	675	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	127/555 - (22%)
Similarity:	226/555 - (40%)	Gaps:	121/555 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 TPERTNLLYFANVATNAKQLKNVSIRRKRTKSKDIKNISIFKKKSTIYEDVFSTDISSKYPPTRE 172
            ||:....:.|.| |....|:..::..:|         :.|:..|:....| |||..|.|......
plant    58 TPDEDGTVNFNN-AEQTSQVGWITYSKK---------VPIWSHKTGKASD-FSTSFSFKIDARNL 111

  Fly   173 SENLKRICREECELLENELCQKEYAIAKRHPVIGMVGVEDCQKLPQHKDCLSLG---ITIEVDKT 234
            |.:...||               :.:|.....:....|.....|...|:..|..   :.:|.|..
plant   112 SADGHGIC---------------FFLAPMGAQLPAYSVGGFLNLFTRKNNYSSSFPLVHVEFDTF 161

  Fly   235 ENCYWE--DGSTYRGVAN-------------VSASGKPC--------------LRWSWLMKEISD 270
            .|..|:  |..::.|:.|             .|.|...|              :.|::.:...||
plant   162 NNPGWDPNDVGSHVGINNNSLVSSNYTSWNASSHSQDICHAKISYDSVTKNLSVTWAYELTATSD 226

  Fly   271 FPELIGQNYCRNPGSVENSPWCF-------VDSSRERII--EL---CDIPKCADKIWIAIVGTTA 323
            ..|....:|..:...|..|...|       .::...|::  ||   .|..|...:|.: ::|.:|
plant   227 PKESSSLSYIIDLAKVLPSDVMFGFIAAAGTNTEEHRLLSWELSSSLDSDKADSRIGL-VIGISA 290

  Fly   324 A--IILIFIIIFAIILF--KRRTIMHYGMRNIHNINTPSADKNIYGNSQLNNAQDAGRGNLGNLS 384
            :  :.|.|::|..::::  |:|......:.|:.:||     |::        .::||
plant   291 SGFVFLTFMVITTVVVWSRKQRKKKERDIENMISIN-----KDL--------EREAG-------- 334

  Fly   385 DHVALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALKENAS 449
                 ..|...::.:...|.|:..     .:||||.||.||:|.|.:.|   ..||:|.|..: |
plant   335 -----PRKFSYKDLVSATNRFSSH-----RKLGEGGFGAVYEGNLKEIN---TMVAVKKLSGD-S 385

  Fly   450 VKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQL 514
            .:.:.:|..|:::||.|:|:|:|.::|....|..:.:::|.:.||.|:..|....|   ..||..
plant   386 RQGKNEFLNEVKIISKLRHRNLVQLIGWCNEKNEFLLIYELVPNGSLNSHLFGKRP---NLLSWD 447

  Fly   515 EFLQIALQISEGMQYLSAHH-----YVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQS 574
            ...:|.|.::..:.||  |.     .:|||:.|.|.:::....||:.||||:| :.:.:.....:
plant   448 IRYKIGLGLASALLYL--HEEWDQCVLHRDIKASNIMLDSEFNVKLGDFGLAR-LMNHELGSHTT 509

  Fly   575 KSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEI 609
            .......:|..|.::.|..:.|||::|||:||.||
plant   510 GLAGTFGYMAPEYVMKGSASKESDIYSFGIVLLEI 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	23/122 (19%)
		KR	235..312	CDD:214527	21/117 (18%)
		PTKc_Ror	404..673	CDD:270642	65/211 (31%)
		Pkinase_Tyr	410..670	CDD:285015	64/205 (31%)
AT5G65600	NP_201363.1	lectin_legume_LecRK_Arcelin_ConA	36..263	CDD:173887	41/230 (18%)
		Pkinase	350..626	CDD:278497	65/210 (31%)
		STKc_IRAK	356..629	CDD:270968	64/199 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050