DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ror and AT5G60320

DIOPT Version :9

Sequence 1:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_200840.1	Gene:	AT5G60320 / 836154	AraportID:	AT5G60320	Length:	675	Species:	Arabidopsis thaliana

Alignment Length:	701	Identity:	148/701 - (21%)
Similarity:	262/701 - (37%)	Gaps:	206/701 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLFTKKDVGSHNVDSRIY-GFQQSSGICHI--------YNGTICRDVLSNA------HVFVSPNL 64
            ||..:::.|.      || ||.|:....|:        .:|.:   .|:||      |.|.....
plant    20 LLSQQEEAGF------IYNGFGQAQAGLHLDGAAKILFPDGLL---QLTNASTQQMGHAFFKKPF 75

  Fly    65 TMNDLEERLKAAYGVI-----KESKDMNANCRMYALPSLCFSSMPICRTPERTNLLYFANVATN- 123
            ..:..|::|..:...:     |...|...........|:.|:.      .:.|..|...|::||
plant    76 KFDSYEKKLSFSTHFVCALVPKPGADGGHGIAFVVSSSIDFTQ------ADPTQYLGLLNISTNG 134

  Fly   124 --AKQLKNVSIRRKRTKSKDIKNISIFKKKSTIYEDVFSTD----ISSKYPPTRESENLKRICRE 182
              :.||  ::|.....:|.:..:|.    |:.:..|:.|.:    .|:.|....:.:|      :
plant   135 SPSSQL--LAIELDTVESAEFDDID----KNHVGIDIKSLNSVESASASYFSNAKGKN------Q 187

  Fly   183 ECELLENELCQ--KEYAIAKRHPVIGMVGVEDCQKLPQHKDCLSLGITIEVDKTENCYWEDGSTY 245
            ..:||..:..|  .:|..|..:..:..:.::.    |.| ..||..|.:    |:  .:.|...:
plant   188 SIKLLSGDPIQIWVDYEGALLNVTVAPLSIQK----PNH-PLLSRSINL----TD--IFPDRKLF 241

  Fly   246 RGVANVSASGKPCLRWSWLMKEISDFPELIGQNYCRNPGSVENSPWCFVDSSRERII-------E 303
            .|.:  :|:|                 .|:...|...        |.|   ||.|::       :
plant   242 FGFS--AATG-----------------TLVSYQYILG--------WSF---SRSRMLLQSLDFSK 276

  Fly   304 LCDIP----KCADKIWIAIVGTTAAIILIFIIIFAIILFKRRTIMHYGMRNI-------HNINTP 357
            |..||    |......:.||.....::::..::..|.|::|:  .:..:|.:       |..:.
plant   277 LPQIPHPKAKQEQTSPLLIVLLMLLVLIMLAVLGGIYLYRRK--KYAEVREVWEKEYSPHRFSY- 338

  Fly   358 SADKNIYGNSQLNNAQDAGRGNLGNLSDHVALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFG 422
               |::|  ...|.....||                                      ||:|.||
plant   339 ---KSLY--KATNRFDKDGR--------------------------------------LGKGGFG 360

  Fly   423 KVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCML 487
            :||:|.|  |:...|  |:|.:..:|....:| |..|:..:..|||:|:|.:||....|....::
plant   361 EVYRGNL--PHVGDI--AVKRVCHDAKQGMKQ-FVAEVVTMGSLKHRNLVPLLGYCRRKGELLLV 420

  Fly   488 FEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQYL--SAHHYV-HRDLAARNCLVNE 549
            .|||:||.|.::|...   |..:||..:.|.|...|:..:.||  .|:..| |||:.|.|.:::.
plant   421 SEYMSNGSLDQYLFHR---EKPALSWSQRLVILKDIASALSYLHTGANQVVLHRDIKASNVMLDS 482

  Fly   550 GLVVKISDFGLSRDIYSSDYYRVQSKSLLPVR-------WMPSESILYGKFTTESDVWSFGVVLW 607
            ....::.|||::|   ..||     ...:||.       :|..|....|. :|.:||::|||::.
plant   483 EFNGRLGDFGMAR---FEDY-----GDSVPVTAAVGTMGYMAPELTTMGT-STRTDVYAFGVLML 538

  Fly   608 EIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSV 658
            |: :.|.:|.......|..:||:                 .:.:||...|:
plant   539 EV-TCGRRPLDPKIPSEKRHLIK-----------------WVCDCWRRDSI 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	38/216 (18%)
		KR	235..312	CDD:214527	15/87 (17%)
		PTKc_Ror	404..673	CDD:270642	73/265 (28%)
		Pkinase_Tyr	410..670	CDD:285015	73/259 (28%)
AT5G60320	NP_200840.1	Lectin_legB	29..278	CDD:365899	56/316 (18%)
AT5G60320	NP_200840.1	STKc_IRAK	354..618	CDD:270968	73/253 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960