DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ror and CRK23

DIOPT Version :9

Sequence 1:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_194062.1	Gene:	CRK23 / 828430	AraportID:	AT4G23310	Length:	830	Species:	Arabidopsis thaliana

Alignment Length:	361	Identity:	97/361 - (26%)
Similarity:	175/361 - (48%)	Gaps:	56/361 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 IWIAIVGTTAAIILIFIIIFAIILFKRRTIM-HYGMRNIHNINTPSADKNIYGNSQLNNAQDAGR 377
            |.||:|.:..|::|:|:.:|::...:|:.:: ...:.|:...:|...:........:..|
plant   432 IIIAVVVSITALLLLFVAVFSVRTKRRKKMIGAIPLLNVKRKDTEVTEPLAENGDSITTA----- 491

  Fly   378 GNLGNLS-DHVALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTTITVAI 441
               |:|. |..|:   :...|..|.||           :||:|.||:||||..    .:.:.||:
plant   492 ---GSLQFDFKAI---VAATNNFLPIN-----------KLGQGGFGEVYKGTF----PSGVQVAV 535

  Fly   442 KALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPT 506
            |.|.: .|.:.:::|:.|:.:::.|:|:|:|.:||..|..|...:::|::.|..|..||...  |
plant   536 KRLSK-TSGQGEREFENEVVVVAKLQHRNLVRLLGYCLEGEEKILVYEFVHNKSLDYFLFDT--T 597

  Fly   507 EGKSLSQLEFLQIALQISEGMQYL---SAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSD 568
            ..:.|......:|...|:.|:.||   |....:||||.|.|.|::..:..|::|||::| |:..|
plant   598 MKRQLDWTRRYKIIGGIARGILYLHQDSRLTIIHRDLKAGNILLDADMNPKVADFGMAR-IFGMD 661

  Fly   569 YYRVQSKSLL-PVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSR 632
            .....::.:: ...:|..|..:||:|:.:|||:||||:::||.|       |..|..:.
plant   662 QTEANTRRVVGTYGYMAPEYAMYGQFSMKSDVYSFGVLVFEIIS-------GMKNSSLY------ 713

  Fly   633 QLLSAPENCPTAVYSLMIECWHEQS---VKRPTFTD 665
            |:..:..|..|..:.|    |...|   :..|:|.|
plant   714 QMDDSVSNLVTYTWRL----WSNGSQLDLVDPSFGD 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568
		KR	235..312	CDD:214527
		PTKc_Ror	404..673	CDD:270642	77/269 (29%)
		Pkinase_Tyr	410..670	CDD:285015	77/263 (29%)
CRK23	NP_194062.1	Stress-antifung	33..129	CDD:279926
		Stress-antifung	145..240	CDD:279926
		Stress-antifung	258..350	CDD:279926
		TyrKc	511..780	CDD:197581	79/271 (29%)
		STKc_IRAK	514..781	CDD:270968	77/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050