DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ror and CRK32

DIOPT Version :9

Sequence 1:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_192887.1	Gene:	CRK32 / 826753	AraportID:	AT4G11480	Length:	656	Species:	Arabidopsis thaliana

Alignment Length:	740	Identity:	173/740 - (23%)
Similarity:	278/740 - (37%)	Gaps:	226/740 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FIVCISLVLLFTKKDVGSHNVDSRIYGFQQSSGICHIYNGTICRDVLSNAHVFVSPNLTMNDLEE 71
            |::.||...:..:|     .|||..:.          .|||..    :|.|:.:| ||..| :..
plant    12 FVLAISFGYVSAQK-----CVDSMFFR----------PNGTYD----TNRHLILS-NLASN-VSS 55

  Fly    72 RLKAAYGVIKESKDMNANCRMYAL--------PSLCFSSMPICRT------PERTNLLYFANVAT 122
            |.....|.:.|..|     |:|||        |.:|...|.|..|      |.:|:       :.
plant    56 RDGYYNGSVGEGPD-----RIYALGLCIPGTDPKVCDDCMQIASTGILQNCPNQTD-------SY 108

  Fly   123 NAKQLKNVSIRRKRTKSKDIKNISIFKKK--------STIYEDVFSTDISSKYPPTRE---SENL 176
            :.:..|.:...|       ..|.|.|.|.        ..:...:|..|::: |..|.|   :..:
plant   109 DWRSQKTLCFVR-------YSNSSFFNKMDLEPTMVIGDLNSGLFQGDLAA-YTRTWEEFMNSMI 165

  Fly   177 KRICREECELLENELCQKEYAIAKRHPVIG---MVGVEDCQKLPQHKDCLSLGITIEVDKTENCY 238
            .|:.|..             .:|...|.||   :..:..|.:.....:|            |.|.
plant   166 TRVGRTR-------------YLADISPRIGSARIYALMQCIRGISSMEC------------ETCI 205

  Fly   239 WEDGSTYRGVANVSASG---KP-C-LRWSWLMKEISDFPELIGQNYCRNPGSVENSPWCFVDSSR 298
            .::...|:...|....|   || | .||.             |..|....|...:.|
plant   206 RDNVRMYQSCCNGFIGGTIRKPVCFFRWD-------------GSEYLGAFGDTPSLP-------- 249

  Fly   299 ERIIELCDIPKCADKIWI---AIVGTTAAIILIFIIIFAIILFKRRTIMHYGMRNIHNINTPSAD 360
                     |...|...|   |||....::: ||:::.|::|..|:      .|..:....|..|
plant   250 ---------PPSPDGKTISTGAIVAVVVSVV-IFVVLLALVLVIRK------RRQSYKTLKPKTD 298

  Fly   361 KNIYGNSQLNNAQDAGRGNLGNLSDHVALNSKL--IERNTLLRINHFTLQDVEFLEELGEGAFGK 423
            .::.....|.             .|.:.|.:..  ..||                .:||:|.||:
plant   299 DDMTSPQSLQ-------------FDFMTLEAATDKFSRN----------------NKLGKGGFGE 334

  Fly   424 VYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLF 488
            ||||.|  ||:|  .||:|.|..|:...| |:||.|:.:::.|:|:|:|.:||..|.::...:::
plant   335 VYKGML--PNET--EVAVKRLSSNSGQGT-QEFKNEVVIVAKLQHKNLVRLLGFCLERDEQILVY 394

  Fly   489 EYMANGDLHEFLISN------SPTEGKSLSQLEFLQIALQISEGMQYL---SAHHYVHRDLAARN 544
            |::.|..|:.||..|      .||:...|.......|...|:.|:.||   |....:|||:.|.|
plant   395 EFVPNKSLNYFLFGNKQKHLLDPTKKSQLDWKRRYNIIGGITRGLLYLHQDSRLTIIHRDIKASN 459

  Fly   545 CLVNEGLVVKISDFGLSRDIYSSDYYRVQS------KSLLPVRWMPSESILYGKFTTESDVWSFG 603
            .|::..:..||:|||::|:      :||..      :.:....:||.|.:.:|:|:|:|||:|||
plant   460 ILLDADMNPKIADFGMARN------FRVDQTEDNTRRVVGTFGYMPPEYVTHGQFSTKSDVYSFG 518

  Fly   604 VVLWEIYS-------YGMQPYYG---------FSNQEVINLIRSRQLLSAPENCPTAVYSLMIEC 652
            |::.||..       |.:....|         ::|...::||..    :..|:|..   ..:|.|
plant   519 VLILEIVCGKKNSSFYKIDDSGGNLVTHVWRLWNNDSPLDLIDP----AIEESCDN---DKVIRC 576

  Fly   653 WH-------EQSVKRPTFTDISNRL 670
            .|       |..|.||..:.|...|
plant   577 IHIGLLCVQETPVDRPEMSTIFQML 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	43/216 (20%)
		KR	235..312	CDD:214527	15/81 (19%)
		PTKc_Ror	404..673	CDD:270642	90/305 (30%)
		Pkinase_Tyr	410..670	CDD:285015	89/297 (30%)
CRK32	NP_192887.1	Stress-antifung	25..122	CDD:279926	30/136 (22%)
		Stress-antifung	<182..234	CDD:279926	12/63 (19%)
		STYKc	324..601	CDD:214568	90/310 (29%)
		STKc_IRAK	327..603	CDD:270968	90/293 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050