DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ror and CRK36

DIOPT Version :9

Sequence 1:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_192358.1	Gene:	CRK36 / 825779	AraportID:	AT4G04490	Length:	658	Species:	Arabidopsis thaliana

Alignment Length:	703	Identity:	165/703 - (23%)
Similarity:	278/703 - (39%)	Gaps:	201/703 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 SPNLT-MNDLEERLKA-AYGVIKESKDMNANC-RMYALPSLCFSSMPI--CR----TPERTNLLY 116
            |||.: :.:||..|.: |..||:|....|.:. .:||| :||.....:  ||    ...|| ||.
plant    36 SPNTSYVENLESLLPSLASNVIRERGFYNVSLDGVYAL-ALCRKHYEVQACRRCVDRASRT-LLT 98

  Fly   117 FANVATNAKQLKNVSIRRKRTKSKDIKNISIFKKKSTIY-------EDVFSTDISSKYPPTRESE 174
            .....|.|          ....|::..|:|...:.|.|:       |.:.:...||..|    |.
plant    99 QCRGKTEA----------YHWDSENDANVSCLVRYSNIHRFGKLKLEPIGNVPHSSLDP----SS 149

  Fly   175 NLKRICRE----------------ECELLENELCQKEYAIAKRH----PVIGM-------VGVED 212
            ||.||.:|                |..:|      |.|.::...    |.:.|       :...|
plant   150 NLTRISQEFAARANRTVEVASTADESSVL------KYYGVSSAEFTDTPEVNMLMQCTPDLSSSD 208

  Fly   213 CQ-------KLPQHKDCLSLGITIEVDKTENCY--WED---GSTYRGVANVSASGK-PCLRWSWL 264
            |.       :..|..:...:|.|:   ...:||  |:|   ...:..:..|.|..: |..|..:.
plant   209 CNHCLRENVRYNQEHNWDRVGGTV---ARPSCYFRWDDYRFAGAFDNLERVPAPPRSPQTRQDYR 270

  Fly   265 MKEISDFPELIGQNYCRNPGSVENSPWCFVDSSRERIIELCDIPKCADKIWIAIVGTTAAIILIF 329
            :|:        |:.:         .||..|                      .:|..|...:.:|
plant   271 VKK--------GRMF---------QPWSVV----------------------VVVFPTGINLAVF 296

  Fly   330 IIIFAIILFKRRTIMHYGMRNIHNINTPSADKNIYGNSQLNNAQDAG-----RGNLGNLSDHVAL 389
            :   |.:|..||      ||           :.||  :::|...|:.     |.:||.:
plant   297 V---AFVLAYRR------MR-----------RRIY--TEINKNSDSDGQATLRFDLGMI------ 333

  Fly   390 NSKLIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQ 454
                     |:..|.|:|::     :||:|.||.||||.|....:    :|:|.| ...|.:.:.
plant   334 ---------LIATNEFSLEN-----KLGQGGFGSVYKGILPSGQE----IAVKRL-AGGSGQGEL 379

  Fly   455 DFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKS--LSQLEFL 517
            :||.|:.|::.|:|:|:|.:||.........:::|::.|..|..|:..    |.|.  |:.....
plant   380 EFKNEVLLLTRLQHRNLVKLLGFCNEGNEEILVYEHVPNSSLDHFIFD----EDKRWLLTWDVRY 440

  Fly   518 QIALQISEGMQYL---SAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLL- 578
            :|...::.|:.||   |....:||||.|.|.|::..:..|::|||::| :::.|..|.::..::
plant   441 RIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEMNPKVADFGMAR-LFNMDETRGETSRVVG 504

  Fly   579 PVRWMPSESILYGKFTTESDVWSFGVVLWEIYS---------YGMQPYYGFSN--QEVINLIRSR 632
            ...:|..|.:.:|:|:.:|||:||||:|.|:.|         .|: |.:.:..  :..:..|...
plant   505 TYGYMAPEYVRHGQFSAKSDVYSFGVMLLEMISGEKNKNFETEGL-PAFAWKRWIEGELESIIDP 568

  Fly   633 QLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTW--HEGHFKASNP 683
            .|...|.|....:..:.:.|..|.:.||||.    |.:.||  .:|.|....|
plant   569 YLNENPRNEIIKLIQIGLLCVQENAAKRPTM----NSVITWLARDGTFTIPKP 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	49/216 (23%)
		KR	235..312	CDD:214527	13/82 (16%)
		PTKc_Ror	404..673	CDD:270642	79/285 (28%)
		Pkinase_Tyr	410..670	CDD:285015	77/276 (28%)
CRK36	NP_192358.1	Stress-antifung	29..124	CDD:279926	27/99 (27%)
		Stress-antifung	162..242	CDD:279926	13/88 (15%)
		STYKc	341..606	CDD:214568	79/284 (28%)
		STKc_IRAK	346..606	CDD:270968	78/274 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050