DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ror and AT3G45330

DIOPT Version :9

Sequence 1:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_190119.1	Gene:	AT3G45330 / 823671	AraportID:	AT3G45330	Length:	682	Species:	Arabidopsis thaliana

Alignment Length:	743	Identity:	143/743 - (19%)
Similarity:	268/743 - (36%)	Gaps:	228/743 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FIVC-ISLVLLFTKKDVGSHNVDSRIY-GFQQ--------------SSGICHIYNGTICRDVLSN 55
            |::| ::|:...:::|:      |.|| ||.|              ..|:..:.|.|    ....
plant    12 FLICFVNLISFSSQQDL------SFIYNGFNQDQTNLNLDGSAKFLQDGLLQLTNAT----TQQK 66

  Fly    56 AHVFVSPNLTMNDLEERLKAAYGVIKESKDMNANCRMYALP------SLCF---SSMPICRTPER 111
            .|.|.:..........:        ..|...:..|.:...|      .:.|   |||.:.:. :.
plant    67 GHAFFNRPFEFGSASSQ--------SPSFSTHFVCALVPKPGVDGGHGIAFVLSSSMDLTQA-DP 122

  Fly   112 TNLLYFANVATNAKQLKNV------SIRRKRTKSKDIKNISIFKKKSTIYEDVFSTDISSKYPPT 170
            |..|...|::||.....::      :::......:|..::.|.:......|..     |:.|...
plant   123 TQYLGLFNISTNGSPSSHLLAIELDTVQSAEFDDRDKNHVGIDENSLQSVESA-----SASYYSD 182

  Fly   171 RESENLKRICREECELLENELCQKEYAIAKRHPVIGMVGVED-----------CQKLPQHKDCLS 224
            :|.:|      :..:||..:            |:...:..||           .||  ..|..||
plant   183 KEGKN------KSLKLLSGD------------PIQVWIDYEDTLLNVTLAPLKTQK--PSKPLLS 227

  Fly   225 LGITIEVDKTENCYWEDGSTYRGVANVSASGKPCLRWSWLMKEISDFPELIGQNYCRNPGSVENS 289
            :.|.:      ...:.|...:.|.:..:.|             :..:..::|.::.||...:::
plant   228 ITINL------TAIFPDRKAFIGFSAATGS-------------LISYQYILGWSFSRNRALLQS- 272

  Fly   290 PWCFVDSSRERIIELCDIPKCADKIWIAIVGTTAAIILIFIIIFAII---------LFKRRTIMH 345
                :|.|:   :.....||..:|        |:.::::.:||.|||         |::|:....
plant   273 ----LDISK---LPTVPRPKKPEK--------TSPLLIVLLIILAIIVMVVVGGFYLYRRKKYAE 322

  Fly   346 --------YG-MRNIHNINTPSADKNIYGNSQLNNAQDAGRGNLGNLSDHVALNSKLIERNTLLR 401
                    || :|..:        |::|..::..|..  ||
plant   323 VREPWEKPYGPLRYSY--------KSLYKATRGFNKD--GR------------------------ 353

  Fly   402 INHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDL 466
                          ||.|.||:||||.|    .....:|:|.|..:|....:| |..|:..:..|
plant   354 --------------LGRGGFGEVYKGTL----PILGDIAVKRLSHDAEQGMKQ-FVAEVVTMGSL 399

  Fly   467 KHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQYL- 530
            :|:|:|.:||....|....::.:||..|.:.::|...   :...||..:.:.|...|:..:.||
plant   400 QHKNLVPLLGYCRRKGELLLVSKYMEGGSVDQYLFHG---DKPPLSWSQRVSILRDIASALCYLH 461

  Fly   531 --SAHHYVHRDLAARNCLVNEGLVVKISDFGLSR-DIYSSDYYRVQSKSLLPVRWMPSESILYGK 592
              ::...:|||:.|.|.::|..|...:.|||::| |.:.|:.  ..:.::..:.:|..|....|.
plant   462 TGASQVVLHRDIKASNVMLNGNLQGFLGDFGMARFDDHGSNL--SATAAVGTIGYMALELTSTGT 524

  Fly   593 FTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQS 657
             :|.:||::||..:.|: :.|.:|:......|..:|::                 .:.|||.|.|
plant   525 -STRTDVYAFGAFMLEV-TCGRRPFDPAMPVEKRHLVK-----------------WVCECWREGS 570

  Fly   658 VKRPTFTDISNRLKTWHEGHFKASNPEM 685
                    :.|.:.|...|.|.....||
plant   571 --------LVNAVDTRLRGKFVPGEVEM 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	34/214 (16%)
		KR	235..312	CDD:214527	10/76 (13%)
		PTKc_Ror	404..673	CDD:270642	66/272 (24%)
		Pkinase_Tyr	410..670	CDD:285015	66/263 (25%)
AT3G45330	NP_190119.1	Lectin_legB	27..279	CDD:278564	50/322 (16%)
		PKc_like	354..618	CDD:304357	71/274 (26%)
		TyrKc	354..616	CDD:197581	71/274 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I2087
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050