| Sequence 1: | NP_476962.1 | Gene: | Ror / 34367 | FlyBaseID: | FBgn0010407 | Length: | 685 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002520.2 | Gene: | NTRK1 / 4914 | HGNCID: | 8031 | Length: | 796 | Species: | Homo sapiens |
| Alignment Length: | 552 | Identity: | 189/552 - (34%) |
|---|---|---|---|
| Similarity: | 262/552 - (47%) | Gaps: | 119/552 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 224 SLGITI-----EVDKTENCYWEDGSTYRGVANV-------------------------SASGKPC 258
Fly 259 --LRWSW---LMKEIS----DFPELIGQNYCRN-------PGSVENSPWC------FVDSSRERI 301
Fly 302 IELCDIP----------------------------KCADKIWIAIVGTTAAIILIFIIIFAIILF 338
Fly 339 KRRTIMHYGMRNIHNINTP-----------SADKNIYGNSQLNNAQDAGRGNLGNLSDHVALNSK 392
Fly 393 LIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQL--LQPNKTTITVAIKALKENASVKTQQD 455
Fly 456 FKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLE----- 515
Fly 516 ------FLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQS 574
Fly 575 KSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPE 639
Fly 640 NCPTAVYSLMIECWHEQSVKRPTFTDISNRLK 671 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ror | NP_476962.1 | CRD_TK_ROR_like | 39..228 | CDD:143568 | 3/3 (100%) |
| KR | 235..312 | CDD:214527 | 22/151 (15%) | ||
| PTKc_Ror | 404..673 | CDD:270642 | 144/281 (51%) | ||
| Pkinase_Tyr | 410..670 | CDD:285015 | 140/272 (51%) | ||
| NTRK1 | NP_002520.2 | leucine-rich repeat | 68..92 | CDD:275378 | |
| LRR 1 | 90..113 | ||||
| LRR_8 | 92..150 | CDD:290566 | |||
| leucine-rich repeat | 93..116 | CDD:275378 | |||
| LRR 2 | 116..137 | ||||
| leucine-rich repeat | 117..139 | CDD:275378 | |||
| leucine-rich repeat | 140..152 | CDD:275378 | |||
| TPKR_C2 | 151..192 | CDD:293525 | |||
| Ig_TrkABC_d4 | 195..282 | CDD:143173 | 7/35 (20%) | ||
| Ig_TrKABC_d5 | 299..379 | CDD:143172 | 16/79 (20%) | ||
| Interaction with SQSTM1. /evidence=ECO:0000250 | 469..490 | 6/24 (25%) | |||
| PTKc_TrkA | 504..783 | CDD:270674 | 144/281 (51%) | ||
| Pkinase_Tyr | 510..781 | CDD:285015 | 140/272 (51%) | ||
| DXXLL. /evidence=ECO:0000269|PubMed:26446845 | 537..541 | 0/3 (0%) | |||
| DXXLL. /evidence=ECO:0000269|PubMed:26446845 | 607..611 | 1/3 (33%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG1026 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||