Protein Alignment me31B and TIF1

DIOPT Version :10

• Sequence 1: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_012985.3
• Gene: TIF1 / 853933
• SGDID: S000001767
• Length: 395
• Species: Saccharomyces cerevisiae
• Alignment Length: 369
• Identity: 146/369 - (39%)
• Similarity: 224/369 - (60%)
• Gaps: 3/369 - (0%)

  Fly    59 EFEEFCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIPVLEQIDPT 123
            :|::..|...||.|:|..|:|.||.||:.||...:.|.||||:|::||||||.:.|..|::||.:
Yeast    23 KFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTS 87

  Fly   124 KDYIQALVMVPTRELALQTSQICIELAKHLDIRVMVTTGGTILKDDILRIYQKVQLIIATPGRIL 188
            ....|||::.||||||||..::.:.||.|:||:|....|||...:|...: :..|:::.||||:.
Yeast    88 VKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGL-RDAQIVVGTPGRVF 151

  Fly   189 DLMDKKVADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHL 253
            |.:.::.......::.:|||||::||..|:..:..:...||...|::|.|||.|..|.....|.:
Yeast   152 DNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFM 216

  Fly   254 REPYEINL-MEELTLKGVTQYYAFVQERQ-KVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKIT 316
            |.|..|.: .:||||:|:.|:|..|:|.: |..||..|:..:.:.|::||||:.::||.|..|:.
Yeast   217 RNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLR 281

  Fly   317 ELGYCCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYLH 381
            ...:....|::.:.|..|:.:..:||.|..|.|:.:||..||||||.|::|||:|.|...|.|:|
Yeast   282 NDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIH 346

  Fly   382 RIGRSGRFGHLGIAINLITYEDRFDLHRIEKELGTEIKPIPKVI 425
            ||||.||||..|:|||.:|.||...:..:||...|:|:.:|..|
Yeast   347 RIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDI 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	146/369 (40%)
		DEADc_DDX6	60..260	CDD:350698	77/199 (39%)
TIF1	NP_012985.3	DEAD-like_helicase_N	10..394	CDD:475120	146/369 (40%)