DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment me31B and RH8

DIOPT Version :9

Sequence 1:	NP_523533.2	Gene:	me31B / 34364	FlyBaseID:	FBgn0004419	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_191975.2	Gene:	RH8 / 828042	AraportID:	AT4G00660	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	408	Identity:	294/408 - (72%)
Similarity:	351/408 - (86%)	Gaps:	2/408 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QIAGNTSDDMGWKSKLKLPPKDNRFKTTDVTDTRGNEFEEFCLKRELLMGIFEKGWERPSPIQEA 87
            ::....|:|  ||::||||..|.|::|.|||.|:|||||::.|||||||||:|||:||||||||.
plant    98 EVIDPNSED--WKARLKLPAPDTRYRTEDVTATKGNEFEDYFLKRELLMGIYEKGFERPSPIQEE 160

  Fly    88 AIPIALSGKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTRELALQTSQICIELAKH 152
            :|||||:|:|:|||||||||||.|:||||||:||...:.|||:::||||||||||||:|.||.||
plant   161 SIPIALTGRDILARAKNGTGKTAAFCIPVLEKIDQDNNVIQAVIIVPTRELALQTSQVCKELGKH 225

  Fly   153 LDIRVMVTTGGTILKDDILRIYQKVQLIIATPGRILDLMDKKVADMSHCRILVLDEADKLLSLDF 217
            |.|:||||||||.|||||:|:||.|.|::.||||||||..|.|..:..|.:||:||||||||.:|
plant   226 LKIQVMVTTGGTSLKDDIMRLYQPVHLLVGTPGRILDLTKKGVCVLKDCSVLVMDEADKLLSQEF 290

  Fly   218 QGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINLMEELTLKGVTQYYAFVQERQK 282
            |..::|:|..||:..|||:||||||:|||:|.::.|..||.||||:||||||:||:||||:||||
plant   291 QPSVEHLISFLPESRQILMFSATFPVTVKDFKDRFLTNPYVINLMDELTLKGITQFYAFVEERQK 355

  Fly   283 VHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGYCCYYIHAKMAQAHRNRVFHDFRQGLCR 347
            :|||||||||||||||||||||..||||||||||||||.|:||||||.|.||||||||||.|.||
plant   356 IHCLNTLFSKLQINQSIIFCNSVNRVELLAKKITELGYSCFYIHAKMLQDHRNRVFHDFRNGACR 420

  Fly   348 NLVCSDLFTRGIDVQAVNVVINFDFPRMAETYLHRIGRSGRFGHLGIAINLITYEDRFDLHRIEK 412
            ||||:||||||||:||||||||||||:.|||||||:||||||||||:|:|||||||||:|:|||:
plant   421 NLVCTDLFTRGIDIQAVNVVINFDFPKNAETYLHRVGRSGRFGHLGLAVNLITYEDRFNLYRIEQ 485

  Fly   413 ELGTEIKPIPKVIDPALY 430
            |||||||.||..||.|:|
plant   486 ELGTEIKQIPPHIDQAIY 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PTZ00424	60..422	CDD:185609	270/361 (75%)
		DEADc	60..260	CDD:238167	132/199 (66%)
		HELICc	270..398	CDD:238034	108/127 (85%)
RH8	NP_191975.2	DEADc_DDX6	133..333	CDD:350698	132/199 (66%)
RH8	NP_191975.2	SF2_C_DEAD	343..472	CDD:350174	109/128 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	225	1.000	Domainoid score	I685
eggNOG	1	0.900	-	-		E2759_KOG0326
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3238
Inparanoid	1	1.050	604	1.000	Inparanoid score	I216
OMA	1	1.010	-	-		QHG53572
OrthoDB	1	1.010	-	-		D583315at2759
OrthoFinder	1	1.000	-	-		FOG0003076
OrthoInspector	1	1.000	-	-		otm2863
orthoMCL	1	0.900	-	-		OOG6_101887
Panther	1	1.100	-	-	O	PTHR47960
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2050
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840