Protein Alignment me31B and Ddx25

DIOPT Version :10

• Sequence 1: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_113818.2
• Gene: Ddx25 / 58856
• RGDID: 68381
• Length: 483
• Species: Rattus norvegicus
• Alignment Length: 484
• Identity: 155/484 - (32%)
• Similarity: 247/484 - (51%)
• Gaps: 82/484 - (16%)

  Fly     3 TEKLNSGHTNLTS-----KGI----INDLQIAGNTSDDMGWKSKLKLPPKDNRFKTTDVTDTRGN 58
            :|:|||..:||..     :||    :.::..:.||.:|            |:.   .||.|...|
  Rat    15 SERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEED------------DDE---DDVVDLAAN 64

  Fly    59 E---------------------------------FEEFCLKRELLMGIFEKGWERPSPIQEAAIP 90
            .                                 |||..||.|||.||:..|:.|||.|||.|:|
  Rat    65 SLLNKLIRQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALP 129

  Fly    91 IALS--GKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTRELALQTSQICIELAKH- 152
            :.|:  .::::|::::|||||.|:.:.:|.:::..:.:.|.|.:.||.||||||.::...:.|.
  Rat   130 MMLAHPPQNLIAQSQSGTGKTAAFVLAMLNRVNALELFPQCLCLAPTYELALQTGRVVERMGKFC 194

  Fly   153 LDIRVMVTTGGTILK--DDILRIYQKVQLIIATPGRILD-LMDKKVADMSHCRILVLDEADKLLS 214
            :|:.||....|..:.  .|:.:     |::|.|||.:|| ...:|:.|::..|:.||||||  :.
  Rat   195 VDVEVMYAIRGNRIPRGTDVTK-----QIVIGTPGTVLDWCFKRKLIDLTKIRVFVLDEAD--VM 252

  Fly   215 LDFQGMLDHVI---LKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINL-MEELTLKGVTQYYA 275
            :|.||..|..|   ..||.:.|:|||||||..:|..|.|:.:.:|..|.| .|||||..:.|||.
  Rat   253 IDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNIRQYYV 317

  Fly   276 FVQERQ-KVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGYCCYYIHAKMAQAHRNRVFH 339
            ..:.|: |...|..::..:.|.|:||||.:.:..:.|..::.:.|:....:..::....|..:..
  Rat   318 LCENRKDKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQRASIIQ 382

  Fly   340 DFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMA------ETYLHRIGRSGRFGHLGIAINL 398
            .||.|..:.|:.:::..|||||:.|.:|:|||.|...      |||||||||:||||..|:|.|:
  Rat   383 RFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKGLAFNM 447

  Fly   399 ITYEDRFDLHRIEKELGTEIKPI-PKVID 426
            |..:....|.:|:....:.||.: |:.:|
  Rat   448 IEVDKLPLLMKIQDHFNSSIKQLDPEDMD 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	143/428 (33%)
		DEADc_DDX6	60..260	CDD:350698	79/208 (38%)
Ddx25	NP_113818.2	Nuclear export signal	61..74		1/12 (8%)
		DEAD-like_helicase_N	80..308	CDD:475120	83/234 (35%)
		Q motif	97..125		15/27 (56%)
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:16968703	100..114		9/13 (69%)
		DEAD box	247..250		2/2 (100%)
		SF2_C_DEAD	312..448	CDD:350174	46/135 (34%)