Protein Alignment me31B and DDX43

DIOPT Version :10

• Sequence 1: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: XP_047274937.1
• Gene: DDX43 / 55510
• HGNCID: 18677
• Length: 653
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 124/405 - (30%)
• Similarity: 198/405 - (48%)
• Gaps: 45/405 - (11%)

  Fly    30 DDMGW-KSK-LKLPP-KDNRFKTTDVT---------------------DTRGNE----------F 60
            :.:.| |:| ..||| |.|.:|.:..|                     |.:..|          |
Human   179 EGLKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTF 243

  Fly    61 EE-FCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIP-----VLE- 118
            :: |....|::..|.:.|:::|:|||..|.||.|.|.|::..|:.|||||..|.:|     ||:
Human   244 DDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQP 308

  Fly   119 QIDPTKDYIQALVMVPTRELALQTSQICIELAKHLDIRVMVTTGGTILKDDILRIYQKVQLIIAT 183
            .:...::....||:.||||||||....|.:.: :..:|.:...||....:.|..:.:.|.:||||
Human   309 SLKGQRNRPGMLVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIEELKKGVDIIIAT 372

  Fly   184 PGRILDLMDKKVADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNF 248
            |||:.||......::.:...||||||||:|.:.|:..:..::|.:..|.|.::.|||:|.:|...
Human   373 PGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRL 437

  Fly   249 MEKHLREP--YEINLMEELTLKGVTQYYAFVQERQK-VHCLNTLFSKLQINQSIIFCNSTQRVEL 310
            .:.:|:||  ..:..::.:.:..|.|......|.:| .|....|.|....::.|:|.:.....:.
Human   438 AQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADH 502

  Fly   311 LAKKITELGYCCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRM 375
            |:..:.........:|....|..|.:...:|:.|..|.|:.:||.:||:||..|..|.||||||.
Human   503 LSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRN 567

  Fly   376 AETYLHRIGRSGRFG 390
            .|.|:|||||:||.|
Human   568 IEEYVHRIGRTGRAG 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	115/382 (30%)
		DEADc_DDX6	60..260	CDD:350698	71/208 (34%)
DDX43	XP_047274937.1	KH-I_DDX43_DDX53	69..134	CDD:411858
		SrmB	242..>582	CDD:440279	111/340 (33%)