DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment me31B and CG7878

DIOPT Version :9

Sequence 1:	NP_523533.2	Gene:	me31B / 34364	FlyBaseID:	FBgn0004419	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_649767.1	Gene:	CG7878 / 40959	FlyBaseID:	FBgn0037549	Length:	703	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	127/397 - (31%)
Similarity:	211/397 - (53%)	Gaps:	34/397 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KSKL-KLPPKDNRFKTTDVTDTRGNE-----------FEE-FCLKRELLMGIFEKGWERPSPIQE 86
            ||:: ::..::|:...:.|.:.:..|           ||: |....::|..|.:.|:.:|||||.
  Fly   247 KSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQCFAEYPDMLEEITKMGFSKPSPIQS 311

  Fly    87 AAIPIALSGKDVLARAKNGTGKTGAYCIPVL----EQIDP--TKDYIQALVMVPTRELALQTSQI 145
            .|.||.|.|.|::..|:.|||||.|:.:|.:    .|..|  |:.....||:.|||||||   ||
  Fly   312 QAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRGGANVLVLAPTRELAL---QI 373

  Fly   146 CIELAKH--LDIRVMVTTGGTILKDDILRIYQKVQLIIATPGRILDLMDKKVADMSHCRILVLDE 208
            .:|:.|:  ..::.:...||......|..:.:..::||.||||:.||:...|.|:|....|||||
  Fly   374 EMEVKKYSFRGMKAVCVYGGGNRNMQISDLERGAEIIICTPGRLNDLIMANVIDVSTITYLVLDE 438

  Fly   209 ADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYE--INLMEELTLKGVT 271
            ||::|.:.|:..:..|:|.:..|.|.::.|||:|..|:...:.:::.|.:  :..::......|.
  Fly   439 ADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSYMKNPIQVCVGSLDLAATHSVK 503

  Fly   272 QYYAFVQERQKVHCLNTLFSKLQINQS-----IIFCNSTQRVELLAKKITELGYCCYYIHAKMAQ 331
            |....:::  .:...||:.|.:: |.|     ||||....|.:.|:.::|..|:....||....|
  Fly   504 QIIKLMED--DMDKFNTITSFVK-NMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRDQ 565

  Fly   332 AHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYLHRIGRSGRFGHLGIAI 396
            ..|.:...|.:.|:.|.||.:|:.:||:|::.:..|||:|||...|.|:||:||:||.|..|.:|
  Fly   566 MDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSI 630

  Fly   397 NLITYED 403
            :..|.||
  Fly   631 SFFTRED 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PTZ00424	60..422	CDD:185609	122/360 (34%)
		DEADc	60..260	CDD:238167	74/210 (35%)
		HELICc	270..398	CDD:238034	45/132 (34%)
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	72/203 (35%)
		DEXDc	298..505	CDD:214692	71/209 (34%)
		Helicase_C	514..624	CDD:278689	40/110 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840