DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment me31B and CG5800

DIOPT Version :9

Sequence 1:	NP_523533.2	Gene:	me31B / 34364	FlyBaseID:	FBgn0004419	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_573230.1	Gene:	CG5800 / 32742	FlyBaseID:	FBgn0030855	Length:	826	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	125/417 - (29%)
Similarity:	205/417 - (49%)	Gaps:	40/417 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 KDNRFKTTDVTDTRGNEFEEFCLKRELLMGIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTG 107
            :|.:.|..::..|...:|.:|.|.::....:.|..:..|:.:|..:|..||.|||||..|..|:|
  Fly    57 QDLKTKYAEIDATAIKKFAQFPLSKKTQKALAESKFVHPTQVQRDSIGPALQGKDVLGAAITGSG 121

  Fly   108 KTGAYCIPVLEQIDPTK----DYIQALVMVPTRELALQTSQICIELAKHLDIRVMVTTGGTILKD 168
            ||.|:.|||||.:...|    |.:.|:::.||||||.|..:...::.||.|....:..||..||.
  Fly   122 KTLAFLIPVLEHLFMNKWSRTDGVGAIIISPTRELAYQIFETLKKVGKHHDFSAGLIIGGKNLKF 186

  Fly   169 DILRIYQKVQLIIATPGRILDLMDKK-VADMSHCRILVLDEADKLLSLDFQGMLDHVILKLPKDP 232
            :..|:.| ..::|.||||:|..||:. :.:.|...:|||||||:.|.:.||..|:.:|...|...
  Fly   187 ERTRMDQ-CNILICTPGRLLQHMDENPLFNTSTMEMLVLDEADRCLDMGFQKTLNSIIENFPPVR 250

  Fly   233 QILLFSATFPLTVKNFMEKHLREPYEIN-----------------------LMEELTLKGVTQYY 274
            |.||||||...||::....:|::|..:.                       .:.||    :.|.|
  Fly   251 QTLLFSATQTNTVQDLARLNLKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPEL----LQQSY 311

  Fly   275 AFVQERQKVHCLNTLFSKLQINQSII-FCNSTQRVELLAKKITEL--GYCCYYIHAKMAQAHRNR 336
            ..:....|:..|.: |.|..:.|.|| |..|.::.:.|.:...:|  |.....::..:.|..|..
  Fly   312 VVLNLEDKITMLWS-FIKNHLKQKIIVFVASCKQAKYLYEIFCKLRPGSPLLALYGTLHQDRRIA 375

  Fly   337 VFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYLHRIGRSGRFGHLGIAINLIT- 400
            ::.||.:.....:..:|:.:||:|..|||.|:..|.|.....|:||.|||.|....|..:.::|
  Fly   376 IYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVLTP 440

  Fly   401 YEDRFDLHRIEKELGTEIKPIPKVIDP 427
            .|:.:.:..::::|..:|:.:.  |||
  Fly   441 SEEEYMISALKEQLNIDIRCVQ--IDP 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PTZ00424	60..422	CDD:185609	119/393 (30%)
		DEADc	60..260	CDD:238167	77/204 (38%)
		HELICc	270..398	CDD:238034	36/130 (28%)
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	125/417 (30%)
		DEADc	74..277	CDD:238167	77/203 (38%)
		HELICc	311..437	CDD:238034	35/126 (28%)
		DUF4217	474..530	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451431
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840