Protein Alignment me31B and Ddx25

DIOPT Version :10

• Sequence 1: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_038960.2
• Gene: Ddx25 / 30959
• MGIID: 1353582
• Length: 484
• Species: Mus musculus
• Alignment Length: 489
• Identity: 157/489 - (32%)
• Similarity: 246/489 - (50%)
• Gaps: 91/489 - (18%)

  Fly     3 TEKLNSGHTNLTS-----KGI----INDLQIAGNTSDDMGWKSKLKLPPKDNRFKTTDVTDTRGN 58
            :|:|||..:||..     :||    :.::..:.||.||           .|:.   .||.|...|
Mouse    15 SERLNSHFSNLVHPRKNLRGIRSTTVPNIDGSLNTEDD-----------DDDE---DDVVDLAAN 65

  Fly    59 E---------------------------------FEEFCLKRELLMGIFEKGWERPSPIQEAAIP 90
            .                                 |||..||.|||.||:..|:.|||.|||.|:|
Mouse    66 SLLNKLIRQSLIESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALP 130

  Fly    91 IALS--GKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTRELALQTSQICIELAKH- 152
            :.|:  .::::|::::|||||.|:.:.:|.:::..:.:.|.|.:.||.||||||.::...:.|.
Mouse   131 MMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVERMGKFC 195

  Fly   153 LDIRVM-------VTTGGTILKDDILRIYQKVQLIIATPGRILD-LMDKKVADMSHCRILVLDEA 209
            :|:.||       :..|..:.|          |:||.|||.:|| ...:|:.|::..|:.|||||
Mouse   196 VDVEVMYAIRGNRIPRGTEVTK----------QIIIGTPGTVLDWCFKRKLIDLTKIRVFVLDEA 250

  Fly   210 DKLLSLDFQGMLDHVI---LKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINL-MEELTLKGV 270
            |  :.:|.||..|..|   ..||.:.|:|||||||..:|..|.|:.:.:|..|.| .|||||..:
Mouse   251 D--VMIDTQGFSDQSIRIQRALPSECQMLLFSATFEDSVWQFAERIIPDPNVIKLRKEELTLNNI 313

  Fly   271 TQYYAFVQERQ-KVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGYCCYYIHAKMAQAHR 334
            .|||...:.|: |...|..::..:.|.|:||||.:.:..:.|..::.:.|:....:..::....|
Mouse   314 RQYYVLCENRKGKYQALCNIYGGITIGQAIIFCQTRRNAKWLTVEMMQDGHQVSLLSGELTVEQR 378

  Fly   335 NRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMA------ETYLHRIGRSGRFGHLG 393
            ..:...||.|..:.|:.:::..|||||:.|.:|:|||.|...      |||||||||:||||..|
Mouse   379 ASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVNQSEEPDYETYLHRIGRTGRFGKKG 443

  Fly   394 IAINLITYEDRFDLHRIEKELGTEIKPI-PKVID 426
            :|.|:|..:....|.:|:....:.||.: |:.:|
Mouse   444 LAFNMIEVDKLPLLMKIQDHFNSNIKQLDPEDMD 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	144/433 (33%)
		DEADc_DDX6	60..260	CDD:350698	80/213 (38%)
Ddx25	NP_038960.2	Nuclear export signal. /evidence=ECO:0000250	62..75		1/12 (8%)
		DEAD-like_helicase_N	81..309	CDD:475120	84/239 (35%)
		Q motif	98..126		15/27 (56%)
		Nuclear localization signal. /evidence=ECO:0000250	101..115		9/13 (69%)
		DEAD box	248..251		2/2 (100%)
		SF2_C_DEAD	313..449	CDD:350174	46/135 (34%)