Protein Alignment me31B and Ddx19b

DIOPT Version :10

• Sequence 1: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001177715.1
• Gene: Ddx19b / 234733
• MGIID: 2148251
• Length: 494
• Species: Mus musculus
• Alignment Length: 436
• Identity: 151/436 - (34%)
• Similarity: 240/436 - (55%)
• Gaps: 35/436 - (8%)

  Fly     3 TEKLNSGH-TNLTSKGIINDLQIAGNTSDDMGWKSKLKLPPKDNRFKTTDVTDTRGNEFEEFCLK 66
            |||..... .:..::.::|.| |..|..|:......|:..|....:..        ..|||..||
Mouse    60 TEKTEEDEKEDRAAQSLLNKL-IRSNLVDNTNQVEVLQRDPSSPLYSV--------KSFEELRLK 115

  Fly    67 RELLMGIFEKGWERPSPIQEAAIPIALS--GKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQA 129
            .:||.|::..|:.|||.|||.|:|:.|:  .::::|::::|||||.|:.:.||.|::|...:.|.
Mouse   116 PQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAVLSQVEPANKFAQC 180

  Fly   130 LVMVPTRELALQTSQICIELAK-HLDIRVMVTTGGTILKDDILRIYQKV--QLIIATPGRILDLM 191
            |.:.||.||||||.::..::.| :.::::.....|..|:..     |||  |::|.|||.:||..
Mouse   181 LCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG-----QKVSEQIVIGTPGTVLDWC 240

  Fly   192 DK-KVADMSHCRILVLDEADKLLSLDFQGMLDHVI---LKLPKDPQILLFSATFPLTVKNFMEKH 252
            .| |..|....::.||||||.:::.  ||..|..|   ..||::.|:|||||||..:|..|.:|.
Mouse   241 SKLKFIDPKKIKVFVLDEADVMIAT--QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKV 303

  Fly   253 LREPYEINL-MEELTLKGVTQYYAFVQER-QKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKI 315
            :.:|..|.| .||.||..:.|||.....| :|...|..|:..:.|.|::|||::.:....||.::
Mouse   304 VPDPNIIKLKREEETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAEL 368

  Fly   316 TELGYCCYYIHAKMAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFP------R 374
            ::.|:....:..:|....|..|...||:|..:.||.:::..|||||:.|:||||||.|      .
Mouse   369 SKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNP 433

  Fly   375 MAETYLHRIGRSGRFGHLGIAINLITYEDRFD-LHRIEKELGTEIK 419
            ..|||||||||:||||..|:|:|::..:...: |:||::....:|:
Mouse   434 DNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	141/388 (36%)
		DEADc_DDX6	60..260	CDD:350698	79/208 (38%)
Ddx19b	NP_001177715.1	DEAD-like_helicase_N	90..318	CDD:475120	85/242 (35%)
		SF2_C_DEAD	322..458	CDD:350174	52/135 (39%)