Protein Alignment me31B and Ddx19a

DIOPT Version :10

• Sequence 1: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_031942.2
• Gene: Ddx19a / 13680
• MGIID: 99526
• Length: 478
• Species: Mus musculus
• Alignment Length: 423
• Identity: 148/423 - (34%)
• Similarity: 236/423 - (55%)
• Gaps: 34/423 - (8%)

  Fly    15 SKGIINDLQIAGNTSDDMGWKSKLKLPPKDNRFKTTDVTDTRGNEFEEFCLKRELLMGIFEKGWE 79
            ::.::|.| |..|..|:......|:..|....:..        ..|||..||.:||.|::..|:.
Mouse    57 AQSLLNKL-IRSNLVDNTNQVEVLQRDPSSPLYSV--------KSFEELRLKPQLLQGVYAMGFN 112

  Fly    80 RPSPIQEAAIPIALS--GKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTRELALQT 142
            |||.|||.|:|:.|:  .::::|::::|||||.|:.:.:|.:::|...|.|.|.:.||.||||||
Mouse   113 RPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPADRYPQCLCLSPTYELALQT 177

  Fly   143 SQICIELAK-HLDIRVMVTTGGTILKDDILRIYQKV--QLIIATPGRILDLMDK-KVADMSHCRI 203
            .::..::.| |.::::.....|..|:..     |||  |::|.|||.:||...| |..|....::
Mouse   178 GKVIEQMGKFHPELKLAYAVRGNKLERG-----QKVSEQIVIGTPGTVLDWCSKLKFIDPKKIKV 237

  Fly   204 LVLDEADKLLSLDFQGMLDHVI---LKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINL-MEE 264
            .||||||.:::.  ||..|..|   ..||::.|:|||||||..:|..|.:|.:.:|..|.| .||
Mouse   238 FVLDEADVMIAT--QGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNIIKLKREE 300

  Fly   265 LTLKGVTQYYAFVQER-QKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGYCCYYIHAK 328
            .||..:.|||.....| :|...|..|:..:.|.|::|||::.:....||.::::.|:....:..:
Mouse   301 ETLDTIKQYYVLCNNREEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGE 365

  Fly   329 MAQAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFP------RMAETYLHRIGRSG 387
            |....|..|...||:|..:.||.:::..|||||:.|:||||||.|      ...|||||||||:|
Mouse   366 MMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTG 430

  Fly   388 RFGHLGIAINLITYEDRFD-LHRIEKELGTEIK 419
            |||..|:|:|::..:...: |:||::....:|:
Mouse   431 RFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIE 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	141/388 (36%)
		DEADc_DDX6	60..260	CDD:350698	79/208 (38%)
Ddx19a	NP_031942.2	N-terminal lobe. /evidence=ECO:0000250	2..299		88/257 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..53
		N-terminal helix. /evidence=ECO:0000250	54..67		3/10 (30%)
		DEAD-like_helicase_N	74..302	CDD:475120	85/242 (35%)
		Q motif	91..119		13/27 (48%)
		DEAD box	241..244		2/2 (100%)
		C-terminal lobe. /evidence=ECO:0000250	300..478		59/164 (36%)
		SF2_C_DEAD	306..442	CDD:350174	52/135 (39%)