Protein Alignment me31B and Ddx6

DIOPT Version :10

• Sequence 1: NP_523533.2
• Gene: me31B / 34364
• FlyBaseID: FBgn0004419
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_031867.1
• Gene: Ddx6 / 13209
• MGIID: 104976
• Length: 483
• Species: Mus musculus
• Alignment Length: 427
• Identity: 306/427 - (71%)
• Similarity: 364/427 - (85%)
• Gaps: 6/427 - (1%)

  Fly    10 HTNLTSKGIINDLQIAGNT---SDDMGWKSKLKLPPKDNRFKTTDVTDTRGNEFEEFCLKRELLM 71
            :|:..:.|.....|....|   .||  ||..|||||||.|.||:|||.|:|||||::||||||||
Mouse    47 NTSTINNGTPQQAQSMAATIKPGDD--WKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLM 109

  Fly    72 GIFEKGWERPSPIQEAAIPIALSGKDVLARAKNGTGKTGAYCIPVLEQIDPTKDYIQALVMVPTR 136
            ||||.|||:||||||.:|||||||:|:||||||||||:|||.||:||::|..||.|||:|:||||
Mouse   110 GIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTR 174

  Fly   137 ELALQTSQICIELAKHL-DIRVMVTTGGTILKDDILRIYQKVQLIIATPGRILDLMDKKVADMSH 200
            |||||.|||||:::||: ..:||.|||||.|:|||:|:...|.::||||||||||:.|.||.:.|
Mouse   175 ELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDH 239

  Fly   201 CRILVLDEADKLLSLDFQGMLDHVILKLPKDPQILLFSATFPLTVKNFMEKHLREPYEINLMEEL 265
            .:::||||||||||.||..:::.:||.|||:.||||:||||||:|:.||..||::||||||||||
Mouse   240 VQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEEL 304

  Fly   266 TLKGVTQYYAFVQERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITELGYCCYYIHAKMA 330
            ||||||||||:|.|||||||||||||:||||||||||||:||||||||||::|||.|:||||||.
Mouse   305 TLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMR 369

  Fly   331 QAHRNRVFHDFRQGLCRNLVCSDLFTRGIDVQAVNVVINFDFPRMAETYLHRIGRSGRFGHLGIA 395
            |.||||||||||.||||||||:||||||||:||||||||||||::||||||||||||||||||:|
Mouse   370 QEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA 434

  Fly   396 INLITYEDRFDLHRIEKELGTEIKPIPKVIDPALYVA 432
            ||||||:|||:|..||::|||||||||..||.:||||
Mouse   435 INLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVA 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
me31B	NP_523533.2	PRK04537	50..>454	CDD:235307	288/384 (75%)
		DEADc_DDX6	60..260	CDD:350698	133/200 (67%)
Ddx6	NP_031867.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..57		2/9 (22%)
		Q motif	96..124		23/27 (85%)
		SrmB	98..461	CDD:440279	273/362 (75%)
		DEAD box	246..249		2/2 (100%)
		Gyf binding. /evidence=ECO:0000250|UniProtKB:P26196	286..316		24/29 (83%)
		RecA-like domain 2. /evidence=ECO:0000250|UniProtKB:P26196	307..483		139/165 (84%)