DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1delta and cars1

DIOPT Version :9

Sequence 1:	NP_609361.1	Gene:	eEF1delta / 34363	FlyBaseID:	FBgn0032198	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001112372.1	Gene:	cars1 / 368284	ZFINID:	ZDB-GENE-030328-29	Length:	824	Species:	Danio rerio

Alignment Length:	318	Identity:	66/318 - (20%)
Similarity:	106/318 - (33%)	Gaps:	120/318 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 WADKSRYDLAEKRFYEG---------PQK------------VTDRSHYSPLVSEIAKAREHIQ-- 51
            |:.....|:::.|.|..         |||            |.|.||       :..||.:|.
Zfish    96 WSPPEGTDISKLRLYNSLTRTKEVFVPQKGNRVLWYCCGPTVYDASH-------MGHARSYISFD 153

  Fly    52 ------NSLEKID-----GVT-LDDGLNSELAKRLAQ---LEGEHKELKTQVSLLNELLTATVKR 101
                  .:..|.|     .:| :||    ::.||..|   ||...::..:...:|.::|||
Zfish   154 ILRRILKNYFKYDVFYCMNITDIDD----KIIKRARQNYLLEQYREKKPSAAQILQDVLTA---- 210

  Fly   102 LETQLKLTNGVSKEPEVEAKKPEANDDDDDVD-LFGSDSEEEDGEAARIREERLAAYAAKKAKKV 165
             .|..|.....:.:|:   ||......|..|| ..|........:||:...::.|....::||.:
Zfish   211 -RTPFKAKLAETTDPD---KKQMLERLDSAVDAALGPLQVAVQSKAAQDSIQKQAQVLLEEAKDL 271

  Fly   166 -----------QIIAKSNIILDVKPWDDE--TDLKVMET------------------EIRKITQD 199
                       |:...|...|..|.|:.|  .|::.:..                  .::||..:
Zfish   272 LSDWLDSQFGSQVTENSIFSLLPKYWEGEYHKDMEALNVLPPDVLTRVSEYVPEIVEFVKKIVDN 336

  Fly   200 G--------LLWGASKF-----------VPVAFGIQK--------LSISCVVEDDKVS 230
            |        :.:..:||           ||.|.|.||        ||||.    |::|
Zfish   337 GYGYESNGSVYFDTAKFDSCPAHSYAKLVPEAVGDQKALQEGEGDLSISA----DRLS 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1delta	NP_609361.1	EF-1_beta_acid	134..>156	CDD:287546	3/21 (14%)
eEF1delta	NP_609361.1	EF1B	168..256	CDD:238181	23/110 (21%)
cars1	NP_001112372.1	GST_C_CysRS_N	2..74	CDD:198343
		PTZ00399	85..822	CDD:240402	66/318 (21%)
		CysRS_core	108..523	CDD:173899	64/306 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2092
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900