DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1delta and EEF1B2

DIOPT Version :9

Sequence 1:	NP_609361.1	Gene:	eEF1delta / 34363	FlyBaseID:	FBgn0032198	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_001032752.1	Gene:	EEF1B2 / 1933	HGNCID:	3208	Length:	225	Species:	Homo sapiens

Alignment Length:	129	Identity:	85/129 - (65%)
Similarity:	103/129 - (79%)	Gaps:	0/129 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 DDDDVDLFGSDSEEEDGEAARIREERLAAYAAKKAKKVQIIAKSNIILDVKPWDDETDLKVMETE 192
            ||||:||||||.|||..||.|:||||||.|.:|||||..::|||:|:|||||||||||:..:|..
Human    97 DDDDIDLFGSDDEEESEEAKRLREERLAQYESKKAKKPALVAKSSILLDVKPWDDETDMAKLEEC 161

  Fly   193 IRKITQDGLLWGASKFVPVAFGIQKLSISCVVEDDKVSIDWLTEEIEKLEDFVQSVDIAAFNKI 256
            :|.|..|||:||:||.|||.:||:||.|.||||||||..|.|.|:|...||:|||:|:||||||
Human   162 VRSIQADGLVWGSSKLVPVGYGIKKLQIQCVVEDDKVGTDMLEEQITAFEDYVQSMDVAAFNKI 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1delta	NP_609361.1	EF-1_beta_acid	134..>156	CDD:287546	16/21 (76%)
eEF1delta	NP_609361.1	EF1B	168..256	CDD:238181	55/87 (63%)
EEF1B2	NP_001032752.1	GST_C_eEF1b_like	<3..62	CDD:198341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	78..115		13/17 (76%)
		EF-1_beta_acid	103..130	CDD:402289	18/26 (69%)
		EF1_GNE	142..225	CDD:395597	52/82 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159541
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2092
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1464823at2759
OrthoFinder	1	1.000	-	-		FOG0001111
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X680
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750