Protein Alignment ova and ewg

DIOPT Version :10

• Sequence 1: NP_609360.2
• Gene: ova / 34362
• FlyBaseID: FBgn0032197
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001245444.1
• Gene: ewg / 30975
• FlyBaseID: FBgn0005427
• Length: 843
• Species: Drosophila melanogaster
• Alignment Length: 674
• Identity: 137/674 - (20%)
• Similarity: 230/674 - (34%)
• Gaps: 179/674 - (26%)

  Fly     1 MDEKDKA----------QHNMISNLPLLFANGYPTSLEKITESQLENFIPFMVQCSLGHINLPKK 55
            |||.|.|          ....:..||.|..:|.||.:||:|::||..|||.|::.|.|.......
  Fly   222 MDELDNALAQQAPPPPQDDPSLFELPGLVIDGIPTPVEKMTQAQLRAFIPLMLKYSTGRGKPGWG 286

  Fly    56 IDCSEPEWWPESAPF-----EIPLKKPKAFVG--NWMEKMKEIVVICYQFH-KSLFLLRFCND-- 110
            .:.:.|.|||:..|:     :...:..|..||  :|...:::||:.||::| :...|..|.:|
  Fly   287 RESTRPPWWPKELPWANVRMDARSEDDKQKVGGISWTHALRKIVINCYKYHGREDLLPTFADDED 351

  Fly   111 -------LAAYEHASLRFIN--NYNSTTSLYDRRNNKLLVTFRNENMSYDRQQKNRKCLLLQKNN 166
                   .:..|...:...|  ..::.|::.....|           |...||.|     :.|.|
  Fly   352 KVNALISQSGDEDEDMELSNPPTIHTVTTMTPPTGN-----------SNQPQQVN-----VVKIN 400

  Fly   167 SSISENVQHMMVE--PPPFDIYLCDNCDAELYSKEAILEHENICC---MEDDVILCDSPEPDNKS 226
            |:.:....|....  |.|..|...:|            :|.....   ....:.:|.:| ..|:.
  Fly   401 SAGTVITTHTAQSNTPAPTIIQSTNN------------QHVTTTATLPASTKIEICQAP-AQNQQ 452

  Fly   227 DGKNEDIEQRNAFLLNFKLQPKFSDNSLSKEKQKTYSFSEETSTETSNRKRRLPSRRNRT-VHSF 290
            ..::......||    ..:||      ::..:.:|...:..:.|.|:...:...:..:.. .|:.
  Fly   453 HHQHHQTHLPNA----VHIQP------VAGGQPQTIQLTTASGTATATAVQTTAAAVSAAQAHAH 507

  Fly   291 SRCSFIPISSPAGQQLLKSTKQTISMDYIAERQERLERFCYTP--LINKSNTKQKYFEKKTNTTV 353
            |:       |.|..|  .|..||::...||..|     .|..|  |.:...|.|....:..:.||
  Fly   508 SQ-------SQAHSQ--SSANQTVTAQQIANAQ-----VCIEPITLSDVDYTTQTVLSQNADGTV 558

  Fly   354 HCTFKKSHEHNYHIYSFPRRQFVKRRDTTENFLFLNSPLIKQCRPISVRLKKISEHVMEEQNHTA 418
            ..           |...|                 |:|:|......:.:::.::.....|...|.
  Fly   559 SL-----------IQVDP-----------------NNPIITLPDGTTAQVQGVATLHQGEGGATI 595

  Fly   419 NTKLNIRLTRHNSLNSHWRISPTKEVVVDTIDLCSSDD--------DEQQEP-----AIGSPKRL 470
            .|..::     ..:|.|..:         |:||..:.|        |.|..|     .|..|..:
  Fly   596 QTVQSL-----TDVNGHENM---------TVDLTETQDGQIYITTEDGQGYPVSVSNVISVPVSM 646

  Fly   471 GSDALTVIKLTHNNRNLYSSRVVEPSKC-APEPESVIVDNSVKPLQQS--------LYIYSNYKA 526
            ....:..::....|.        :.:.| ||......::.|......|        :..||...|
  Fly   647 YQSVMANVQQIQTNS--------DGTVCLAPMQVDTSINRSTSTAASSSSSLGNGGVQCYSLISA 703

  Fly   527 -NSVISRCTVDSIANHSLVGS---LSTSNTFADSEGHRKEYNQENCNFSKN-------LVALTDW 580
             :||:||.:...|.:....|.   |:|  |.:.|.|..   |..||..:.|       :|..|..
  Fly   704 GSSVLSRRSGGVIGHQVTPGERYYLAT--TTSSSLGLN---NNNNCTLANNNNSVKMPIVLATPS 763

  Fly   581 YAHSANSKKSTTNQTTESSTFDAI 604
            ....|| |:||..::|..|..|.:
  Fly   764 IPQVAN-KRSTGKRSTGVSGGDDV 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ova	NP_609360.2	Nrf1_DNA-bind	<15..105	CDD:463112	31/97 (32%)
ewg	NP_001245444.1	Nrf1_DNA-bind	145..347	CDD:463112	37/124 (30%)