Protein Alignment CG5708 and LHX3

DIOPT Version :10

• Sequence 1: NP_609359.1
• Gene: CG5708 / 34361
• FlyBaseID: FBgn0032196
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_055379.1
• Gene: LHX3 / 8022
• HGNCID: 6595
• Length: 402
• Species: Homo sapiens
• Alignment Length: 166
• Identity: 59/166 - (35%)
• Similarity: 80/166 - (48%)
• Gaps: 35/166 - (21%)

  Fly    75 IKVCGGCGDKISDRYLLYALDRYWHNGCLKCHCCGAMLAEVGSSCFTRRGLILCKKDYSSMFGCS 139
            |.:|.||...|.||::|.||||:||:.||||..|...|||   .||:|...:.||.|:...||..
Human    33 IPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFGTK 94

  Fly   140 GVCSGCGETIPPSELVAKALTGINNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDR-YTMLG 203
              |:.|...|||:::|.:|.                :.|:||.||:|..|...|..||. |.|..
Human    95 --CAACQLGIPPTQVVRRAQ----------------DFVYHLHCFACVVCKRQLATGDEFYLMED 141

  Fly   204 ASLVCEQDWHKLLKGPANSNGTLGQRKGK--VGRPR 237
            :.|||:.|:.           |..||:.:  ..|||
Human   142 SRLVCKADYE-----------TAKQREAEATAKRPR 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_609359.1	LIM1_LMO4	78..132	CDD:188772	26/53 (49%)
		LIM	142..212	CDD:413332	22/70 (31%)
LHX3	NP_055379.1	LIM1_Lhx3b	33..87	CDD:188851	27/56 (48%)
		LIM2_Lhx3_Lhx4	95..150	CDD:188762	22/70 (31%)
		Homeodomain	163..219	CDD:459649	3/4 (75%)