Protein Alignment CG5708 and ISL2

DIOPT Version :10

• Sequence 1: NP_609359.1
• Gene: CG5708 / 34361
• FlyBaseID: FBgn0032196
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_665804.1
• Gene: ISL2 / 64843
• HGNCID: 18524
• Length: 359
• Species: Homo sapiens
• Alignment Length: 160
• Identity: 53/160 - (33%)
• Similarity: 75/160 - (46%)
• Gaps: 24/160 - (15%)

  Fly    77 VCGGCGDKISDRYLL-YALDRYWHNGCLKCHCCGAMLAEVGSSCFTRRGLILCKKDYSSMFGCSG 140
            :|.|||.:|.|:::| .:.|..||..||||..|...|.|. .:||.|.|...||:||..:||..
Human    26 MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDET-CTCFVRDGKTYCKRDYVRLFGIK- 88

  Fly   141 VCSGCGETIPPSELVAKALTGINNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDRYTMLGAS 205
             |:.|......|:||.:|.                :.|:|:.||.|:.|...|.|||.:::....
Human    89 -CAKCQVGFSSSDLVMRAR----------------DSVYHIECFRCSVCSRQLLPGDEFSLREHE 136

  Fly   206 LVCEQDWHKLLK----GPANSNGTLGQRKG 231
            |:|..|...||:    |...|.|.|...:|
Human   137 LLCRADHGLLLERAAAGSPRSPGPLPGARG 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_609359.1	LIM1_LMO4	78..132	CDD:188772	23/54 (43%)
		LIM	142..212	CDD:413332	18/69 (26%)
ISL2	NP_665804.1	LIM1_Isl	27..81	CDD:188752	23/54 (43%)
		LIM2_Isl2	89..143	CDD:188855	18/69 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..191		5/16 (31%)
		HOX	191..247	CDD:197696
		LIM-binding domain (LID). /evidence=ECO:0000250	272..301
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	326..359