Protein Alignment CG5708 and LHX5

DIOPT Version :10

• Sequence 1: NP_609359.1
• Gene: CG5708 / 34361
• FlyBaseID: FBgn0032196
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_071758.1
• Gene: LHX5 / 64211
• HGNCID: 14216
• Length: 402
• Species: Homo sapiens
• Alignment Length: 149
• Identity: 55/149 - (36%)
• Similarity: 72/149 - (48%)
• Gaps: 25/149 - (16%)

  Fly    78 CGGCGDKISDRYLLYALDRYWHNGCLKCHCCGAMLAEVGSSCFTRRGLILCKKDYSSMFGCSGVC 142
            |.||...|.||:||..|||.||..|::|..|...|:|   .||:|.|.:.||.|:...||..  |
Human     5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSE---KCFSREGKLYCKNDFFRRFGTK--C 64

  Fly   143 SGCGETIPPSELVAKALTGINNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDR-YTMLGASL 206
            :||.:.|.||:||.||.:.                ||||.||:|..|...|..|:. |.:.....
Human    65 AGCAQGISPSDLVRKARSK----------------VFHLNCFTCMVCNKQLSTGEELYVIDENKF 113

  Fly   207 VCEQDW---HKLLKGPANS 222
            ||:.|:   ..|.:|..||
Human   114 VCKDDYLSSSSLKEGSLNS 132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_609359.1	LIM1_LMO4	78..132	CDD:188772	24/53 (45%)
		LIM	142..212	CDD:413332	23/70 (33%)
LHX5	NP_071758.1	LIM1_Lhx1_Lhx5	5..56	CDD:188753	24/53 (45%)
		LIM2_Lhx1_Lhx5	64..119	CDD:188761	23/70 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..186		4/9 (44%)
		Homeodomain	181..237	CDD:459649
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..402
		PHA03378	<301..>392	CDD:223065