DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5708 and LMX1A

DIOPT Version :9

Sequence 1:	NP_001285799.1	Gene:	CG5708 / 34361	FlyBaseID:	FBgn0032196	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001167540.1	Gene:	LMX1A / 4009	HGNCID:	6653	Length:	382	Species:	Homo sapiens

Alignment Length:	152	Identity:	53/152 - (34%)
Similarity:	71/152 - (46%)	Gaps:	26/152 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 VCGGCGDKISDRYLLYALDRYWHNGCLKCHCCGAMLAEVGSSCFTRRGLILCKKDYSSMFGCSGV 141
            ||.||...|.||:||...|.:||..|::|..|...|.   ::||.|...:.||.||..:|...
Human    34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLE---TTCFYRDKKLYCKYDYEKLFAVK-- 93

  Fly   142 CSGCGETIPPSELVAKALTGINNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDRYTMLGASL 206
            |.||.|.|.|:|.|.:|            ||.    |:||.||.|..|...|:.||.:.:....|
Human    94 CGGCFEAIAPNEFVMRA------------QKS----VYHLSCFCCCVCERQLQKGDEFVLKEGQL 142

  Fly   207 VCEQDWHK-----LLKGPANSN 223
            :|:.|:.|     .|..||.|:
Human   143 LCKGDYEKERELLSLVSPAASD 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_001285799.1	LIM1_LMO4	78..132	CDD:188772	20/53 (38%)
CG5708	NP_001285799.1	LIM	142..212	CDD:413332	23/69 (33%)
LMX1A	NP_001167540.1	LIM1_Lmx1a	35..86	CDD:188756	20/53 (38%)
		LIM2_Lmx1a_Lmx1b	94..148	CDD:188764	23/69 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..208		2/4 (50%)
		Homeobox	198..252	CDD:395001
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910