Protein Alignment CG5708 and ISL1

DIOPT Version :10

• Sequence 1: NP_609359.1
• Gene: CG5708 / 34361
• FlyBaseID: FBgn0032196
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_002193.2
• Gene: ISL1 / 3670
• HGNCID: 6132
• Length: 349
• Species: Homo sapiens
• Alignment Length: 139
• Identity: 46/139 - (33%)
• Similarity: 65/139 - (46%)
• Gaps: 20/139 - (14%)

  Fly    74 LIKVCGGCGDKISDRYLL-YALDRYWHNGCLKCHCCGAMLAEVGSSCFTRRGLILCKKDYSSMFG 137
            ||.:|.|||::|.|:|:| .:.|..||..||||..|...|.| ..:||.|.|...||:||..::|
Human    13 LISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDE-SCTCFVRDGKTYCKRDYIRLYG 76

  Fly   138 CSGVCSGCGETIPPSELVAKALTGINNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDRYTML 202
            ..  |:.|......::.|.:|.:.                |:|:.||.|..|...|.|||.:.:.
Human    77 IK--CAKCSIGFSKNDFVMRARSK----------------VYHIECFRCVACSRQLIPGDEFALR 123

  Fly   203 GASLVCEQD 211
            ...|.|..|
Human   124 EDGLFCRAD 132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_609359.1	LIM1_LMO4	78..132	CDD:188772	24/54 (44%)
		LIM	142..212	CDD:413332	17/70 (24%)
ISL1	NP_002193.2	LIM1_Isl	17..71	CDD:188752	24/54 (44%)
		LIM domain	20..73		24/53 (45%)
		LIM2_Isl	79..133	CDD:188760	17/70 (24%)
		LIM domain	82..136		16/67 (24%)
		HOX	181..237	CDD:197696
		Homeodomain	184..243
		LIM-binding domain (LID). /evidence=ECO:0000250	262..291
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..349