Protein Alignment CG5708 and Lhx4

DIOPT Version :10

• Sequence 1: NP_609359.1
• Gene: CG5708 / 34361
• FlyBaseID: FBgn0032196
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_034842.2
• Gene: Lhx4 / 16872
• MGIID: 101776
• Length: 390
• Species: Mus musculus
• Alignment Length: 164
• Identity: 57/164 - (34%)
• Similarity: 80/164 - (48%)
• Gaps: 30/164 - (18%)

  Fly    75 IKVCGGCGDKISDRYLLYALDRYWHNGCLKCHCCGAMLAEVGSSCFTRRGLILCKKDYSSMFGCS 139
            |..|.||...|.|:::|..|||:||:.||||..|...||:   .||:|.|.:.||:|:...||..
Mouse    27 IPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLAD---RCFSRAGSVYCKEDFFKRFGTK 88

  Fly   140 GVCSGCGETIPPSELVAKALTGINNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDR-YTMLG 203
              |:.|.:.|||:::|.||.                :.|:||.||:|..|...|..||. |.|..
Mouse    89 --CTACQQGIPPTQVVRKAQ----------------DFVYHLHCFACIICNRQLATGDEFYLMED 135

  Fly   204 ASLVCEQDWHKLLKGPANSNGTLGQRKGKVGRPR 237
            ..|||::|:.   ....|.:...|.:     |||
Mouse   136 GRLVCKEDYE---TAKQNDDSEAGAK-----RPR 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_609359.1	LIM1_LMO4	78..132	CDD:188772	24/53 (45%)
		LIM	142..212	CDD:413332	23/70 (33%)
Lhx4	NP_034842.2	LIM1_Lhx4	30..81	CDD:188852	24/53 (45%)
		LIM2_Lhx3_Lhx4	89..144	CDD:188762	23/70 (33%)
		Homeodomain	158..214	CDD:459649	3/9 (33%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:Q969G2	161..181		1/1 (100%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:Q969G2	199..211
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	231..253
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..390