Protein Alignment CG5708 and Lhx2

DIOPT Version :10

• Sequence 1: NP_609359.1
• Gene: CG5708 / 34361
• FlyBaseID: FBgn0032196
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_001407283.1
• Gene: Lhx2 / 16870
• MGIID: 96785
• Length: 414
• Species: Mus musculus
• Alignment Length: 241
• Identity: 74/241 - (30%)
• Similarity: 97/241 - (40%)
• Gaps: 80/241 - (33%)

  Fly    40 DTVETNSNISSSQLSFMDESSNDFNNQQLIHSNSLIKVCGGCGDKISDRYLLYALDRYWHNGCLK 104
            ||..|..:|||.:.:                      :|.|||.||||||.|.|:|:.||..|||
Mouse    37 DTETTMPSISSDRAA----------------------LCAGCGGKISDRYYLLAVDKQWHMRCLK 79

  Fly   105 CHCCGAMLAEVGSSCFTRRGLILCKKDYSS--------MFGCSGVCSGCGETIPPSELVAKALTG 161
            |..|...| |...:||::.|.|.||:||.|        .|.... |:.|...|..||:|.:|.
Mouse    80 CCECKLNL-ESELTCFSKDGSIYCKEDYYSPSLHGPHRRFSVQR-CARCHLGISASEMVMRAR-- 140

  Fly   162 INNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDRYTMLGASLVCEQDWHKLLKG--PANSN- 223
                ||          |:||.||:|..|...|..||.:.|..:.:.|...:..||:|  ||:.|
Mouse   141 ----DL----------VYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAHFNH 191

  Fly   224 ------------------GTLGQRK---------GKV--GRPRRSK 240
                              |:.|...         |.|  ||||:.|
Mouse   192 ADVAAAAAAAAAAKSAGLGSAGANPLGLPYYNGVGTVQKGRPRKRK 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_609359.1	LIM1_LMO4	78..132	CDD:188772	28/53 (53%)
		LIM	142..212	CDD:413332	21/69 (30%)
Lhx2	NP_001407283.1	LIM1_Lhx2	43..106	CDD:188853	31/85 (36%)
		LIM2_Lhx2_Lhx9	119..177	CDD:188763	21/74 (28%)
		COG5576	<255..386	CDD:227863
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..278
		Homeodomain	275..331	CDD:459649
		Nuclear localization signal. /evidence=ECO:0000255	315..331
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	336..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	395..414