DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5708 and Lmx1a

DIOPT Version :9

Sequence 1:	NP_001285799.1	Gene:	CG5708 / 34361	FlyBaseID:	FBgn0032196	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_387501.1	Gene:	Lmx1a / 110648	MGIID:	1888519	Length:	382	Species:	Mus musculus

Alignment Length:	206	Identity:	62/206 - (30%)
Similarity:	86/206 - (41%)	Gaps:	55/206 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ENFAPIVIDYRNSNHTKDTVETNSNISSSQLSFMDESSNDFNNQQLIHSNSLIKVCGGCGDKISD 87
            |||             :..:||:::.||                .|..:.|...||.||...|||
Mouse     9 ENF-------------QSAIETSASFSS----------------LLGRAVSPKSVCEGCQRVISD 44

  Fly    88 RYLLYALDRYWHNGCLKCHCCGAMLAEVGSSCFTRRGLILCKKDYSSMFGCSGVCSGCGETIPPS 152
            |:||...|.:||..|::|..|...|.   ::||.|...:.||..|..:|...  |.||.|.|.|:
Mouse    45 RFLLRLNDSFWHEQCVQCASCKEPLE---TTCFYRDKKLYCKYHYEKLFAVK--CGGCFEAIAPN 104

  Fly   153 ELVAKALTGINNIDLQNQQKQIINCVFHLRCFSCAKCGSSLRPGDRYTMLGASLVCEQDWHK--- 214
            |.|.:|            ||.    |:||.||.|..|...|:.||.:.:....|:|:.|:.|
Mouse   105 EFVMRA------------QKS----VYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERE 153

  Fly   215 --LLKGPANSN 223
              .|..||.|:
Mouse   154 LLSLVSPAASD 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5708	NP_001285799.1	LIM1_LMO4	78..132	CDD:188772	21/53 (40%)
CG5708	NP_001285799.1	LIM	142..212	CDD:413332	23/69 (33%)
Lmx1a	NP_387501.1	LIM1_Lmx1a	35..86	CDD:188756	21/53 (40%)
		LIM2_Lmx1a_Lmx1b	94..148	CDD:188764	23/69 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..208		2/4 (50%)
		Homeobox	198..252	CDD:365835
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..286
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910