DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4908 and AFG3

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_010933.1	Gene:	AFG3 / 856737	SGDID:	S000000819	Length:	761	Species:	Saccharomyces cerevisiae

Alignment Length:	169	Identity:	55/169 - (32%)
Similarity:	81/169 - (47%)	Gaps:	28/169 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 IADCQD----------FIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSVCLLNL 257
            :|.|.:          |:|:...||:.|....||.:|.||||.||:....|.|||.......::.
Yeast   290 VAGCDEAKQEIMEFVHFLKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVPFLSVSG 354

  Fly   258 SE-----RGLTDDRLNHLL----NVAPEQSIILLEDIDAAFVSREATPQQKSAFDGLN---RITF 310
            ||     .|:...|:..|.    ::||  |||.:::|||  :.:|.  .:..|..|.|   ..|.
Yeast   355 SEFVEMFVGVGASRVRDLFTQARSMAP--SIIFIDEIDA--IGKER--GKGGALGGANDEREATL 413

  Fly   311 SGLLNCLDGVGSTEARIVFMTTNYIDRLDPALVRPGRID 349
            :.||..:||..:::..:|...||..|.||.||:||||.|
Yeast   414 NQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFD 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	55/169 (33%)
AFG3	NP_010933.1	FtsH_ext	124..215	CDD:377663
AFG3	NP_010933.1	FtsH_fam	223..730	CDD:273520	55/169 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810