DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4908 and AT5G40000

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_198816.1	Gene:	AT5G40000 / 833997	AraportID:	AT5G40000	Length:	470	Species:	Arabidopsis thaliana

Alignment Length:	481	Identity:	128/481 - (26%)
Similarity:	214/481 - (44%)	Gaps:	115/481 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GAGFGLFGVGAAA-----AILRKGLQGGVILFRRHCMITLEVPCRDKSYQWLLKWI--TIRGARK 74
            |..||..|...|:     |.:::       :|..|..||::        ::||...  .....|.
plant     5 GDSFGSIGSSMASLFFLWATIQQ-------IFPDHLKITIK--------EFLLSSFQQLCFAQRV 54

  Fly    75 TQHLS------VETNFVQNDNGTIKTSYDFIPSI--------GKHLFQYKGNWIQ-----VERTR 120
            :.|.:      ||.:|.::|..:...::..|.:.        .|||   :|:.::     |.:..
plant    55 SDHFTNLFSPYVEIHFPESDEYSFNQAFSAIDTYLDSKATDKTKHL---RGSQVKESKGLVLKRN 116

  Fly   121 EQQTLDLHMG--VPWETVTLTAFGNNKGIYFDIL--EEARQLALEA------TEGKTV------- 168
            |.:..|.:.|  |.||.|.    .|:...|:.:.  ..||.|...:      .|||::
plant   117 EAKVRDEYKGANVWWERVV----DNDGNRYYKLTFHNRARTLITNSYIKYVVEEGKSIIVKNKQT 177

  Fly   169 -LYT-------AMGAE-WR--PFGHPRRRRPTGSVVLDRGTSQRIIADCQDFIKSSLWYTQRGIP 222
             |:|       ..|.. ||  .|.||...:   ::.:|....:.|:.|...|.....:|.:.|..
plant   178 RLFTNNLSTQWVFGQNMWRSIEFEHPASFQ---TLAMDPKKKEEIVNDLIAFSNGKEYYKKIGKA 239

  Fly   223 YRRGYLLYGPPGCGKSSFITALAGELEYSVCLLNLSERGLTDDRLNHLLNVAPEQSIILLEDID- 286
            ::||||||||||.|||:.|:|:|..|.|::..|.|: ....:..|..||.....:|||::||||
plant   240 WKRGYLLYGPPGTGKSTMISAMANLLNYNIYDLELT-AVKNNSELKKLLTATSSKSIIVIEDIDC 303

  Fly   287 -AAFVS----REATPQQKSAFDGL--NRITFSGLLNCLDGVGST--EARIVFMTTNYIDRLDPAL 342
             |.|.|    :|:..:::...:..  |.:|.|||||.:||:.|.  :.|||..|||::::|||||
plant   304 SADFTSNRIKKESNSRERYGKEDKDENSVTLSGLLNFIDGIWSACGQERIVVFTTNHLEKLDPAL 368

  Fly   343 VRPGRIDLKEYIGYCTQYQLEEMFKNFFASSDTTKAEEFGKRVNSFGRSASP--AQIQGFFMKHK 405
            :|.||:|:...:.|||....:.:.||:               ::..|..|.|  ::|:....:.|
plant   369 IRRGRMDMHIELSYCTYEAFKILAKNY---------------LDLDGDDAHPLFSEIKALLEETK 418

  Fly   406 LSSPQTVIDSCEDIWENVLDHNKKIN 431
            :|.        .|:.||::..|::|:
plant   419 ISP--------ADVAENLMARNQQID 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980	44/222 (20%)
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	64/161 (40%)
AT5G40000	NP_198816.1	AAA_assoc	29..135	CDD:373025	24/116 (21%)
		RarA	197..>287	CDD:225165	30/93 (32%)
		AAA	244..382	CDD:365803	57/138 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	98	1.000	Domainoid score	I2399
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I1900
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D532729at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2395
orthoMCL	1	0.900	-	-		OOG6_101424
Panther	1	1.100	-	-	O	PTHR23070
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X279
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.870