DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4908 and AT2G18190

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_179411.2	Gene:	AT2G18190 / 816332	AraportID:	AT2G18190	Length:	494	Species:	Arabidopsis thaliana

Alignment Length:	463	Identity:	126/463 - (27%)
Similarity:	194/463 - (41%)	Gaps:	105/463 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LQGGVILFRRHCMITLEVPCRDKSY--QWLLKWIT------------IRGARKTQHLSVETNFVQ 86
            |.|.::|||  .:...|||.|.:||  ..|.::.|            |.|.::.|.......:::
plant    22 LTGFLMLFR--SLFNDEVPERLRSYITDLLNRFFTPKSKNLTMVIDEIIGFKRNQVFDAAEVYLR 84

  Fly    87 NDNG--TIKTSYDFIPSIGKHLFQY--KG------------NWIQVERTREQQTLDLHMGVPWET 135
            |..|  |.:.....:|. .||...|  ||            .|..||...|....:..
plant    85 NKIGPETARLRVGKLPK-QKHFTIYIEKGEEILDTFENSELRWTYVESENEASQKEKR------- 141

  Fly   136 VTLTAFGNNKGIYFDILEEAR-----------QLALEATEGK-----TVLYT-----------AM 173
                        |:::..|.:           .:..|:.|.|     ..||:           ..
plant   142 ------------YYELTFEKKLRDKVMNSYLSHVVAESEETKRDLRAVKLYSRDVRASKDDDGMA 194

  Fly   174 GAEWRPFG--HPRRRRPTGSVVLDRGTSQRIIADCQDFIKSSLWYTQRGIPYRRGYLLYGPPGCG 236
            ||.|....  ||....   ::.:|.|..::||.|.:.|:|...:|.:.|..::||||||||||.|
plant   195 GAGWGCINLEHPSTFE---TLAMDPGAKKKIIDDMERFLKRREFYKRVGKAWKRGYLLYGPPGTG 256

  Fly   237 KSSFITALAGELEYSVCLLNLSERGLTDDRLNHLLNVAPEQSIILLEDID---AAFVSREATPQQ 298
            |||.|.|:|..|::.|..|.||.. ..:.:|..:|.....:||:::||||   |..|.|||...|
plant   257 KSSLIAAMANYLKFDVFDLELSSI-YENAQLKSILLSTTNRSILVIEDIDCSSAEVVDREADEYQ 320

  Fly   299 KSAFDGLNRITFSGLLNCLDGVGST--EARIVFMTTNYIDRLDPALVRPGRIDLKEYIGYCTQYQ 361
            :.......|:|.|||||.:||:.|:  :.||:..|||:.:||||||:||||:|:...:.|||...
plant   321 EYEEGYYGRVTLSGLLNFVDGLWSSFGDERIIVFTTNHKERLDPALLRPGRMDMHINMSYCTGLG 385

  Fly   362 LEEMFKNFFASSDTTK--AEEFGKRVNSFGRSASPAQIQGFFMKHKLSSPQTVIDSCEDIWENVL 424
            ...:..|:........  .||....::|  ...:||::....|:.         |..:.:...|:
plant   386 FRTLVSNYLGLGGLNHPLCEEIEALIDS--TEVTPAELAEELMQE---------DDTDVVLRGVV 439

  Fly   425 D--HNKKI 430
            .  .|:|:
plant   440 SFVENRKV 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980	41/214 (19%)
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	69/156 (44%)
AT2G18190	NP_179411.2	AAA_assoc	37..130	CDD:291061	20/93 (22%)
		P-loop_NTPase	219..>266	CDD:304359	23/46 (50%)
		AAA	244..378	CDD:214640	62/134 (46%)
		AAA	247..380	CDD:278434	60/133 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	98	1.000	Domainoid score	I2399
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I1900
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D532729at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2395
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23070
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X279
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.970