DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4908 and spg7

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_001923118.1	Gene:	spg7 / 794740	ZFINID:	ZDB-GENE-030131-5391	Length:	788	Species:	Danio rerio

Alignment Length:	262	Identity:	68/262 - (25%)
Similarity:	116/262 - (44%)	Gaps:	31/262 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 MGVPWETVTLTAFGNNKGIY--FDILEEARQLALEATEGKTVLYTAMGAEWRPFGHPRRRRPTGS 191
            :.:.|....|...|...|.:  |:.|:.|:...::...||       |..::.....|.
Zfish   256 VAILWYIFRLAGMGGRDGGFSAFNQLKMAKFTIVDGKSGK-------GVSFKDVAGMRE------ 307

  Fly   192 VVLDRGTSQRIIADCQDFIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSVCLLN 256
                   ::..:.:..|::|:...|.|.|....:|.||.|||||||:....|:|.|.:.....:.
Zfish   308 -------AKMEVKEFVDYLKNPDRYLQLGAKVPKGSLLLGPPGCGKTLLAKAVATEAQVPFLAMA 365

  Fly   257 LSE-----RGLTDDRLNHLLNVAPEQS--IILLEDIDAAFVSREATPQQKSAFDGLNRITFSGLL 314
            .||     .||...|:..|...|..::  |:.:::|||  |.::.:.......:.....|.:.||
Zfish   366 GSEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDA--VGKKRSTNMSGFSNTEEEQTLNQLL 428

  Fly   315 NCLDGVGSTEARIVFMTTNYIDRLDPALVRPGRIDLKEYIGYCTQYQLEEMFKNFFASSDTTKAE 379
            ..:||:|:|:..||..:||..|.||.||:||||:|...:|...|..:.:|:|:........|:..
Zfish   429 VEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERKEIFEQHLKILKLTQPA 493

  Fly   380 EF 381
            :|
Zfish   494 DF 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980	11/64 (17%)
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	51/158 (32%)
spg7	XP_001923118.1	FtsH_ext	136..233	CDD:284011
		FtsH_fam	257..738	CDD:273520	68/261 (26%)
		AAA	337..470	CDD:278434	46/134 (34%)
		Peptidase_M41	552..736	CDD:279742
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810