DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4908 and afg3l1

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_005163264.1	Gene:	afg3l1 / 570430	ZFINID:	ZDB-GENE-121214-51	Length:	751	Species:	Danio rerio

Alignment Length:	440	Identity:	100/440 - (22%)
Similarity:	162/440 - (36%)	Gaps:	126/440 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VAGLSSNPYFGAGFGLFGVGAAAAILRKGLQGGVILFRRHCMITLEVPCRD-------------- 57
            :...:::|.|.   ||:||....::      |....|.:.|..| :.| :|
Zfish    24 IRSCAAHPPFS---GLYGVSPLRSV------GKRFTFPQSCYST-DAP-KDAPPPGGGGGGRRGG 77

  Fly    58 -KSY-----QWLLKWITIRGARKTQHLSVETNFVQ--------NDNGTIKTSYDFIPSIGKHLFQ 108
             ||:     |....|    ..|..:||.:..:.|.        .|.|...|..||:     |.:.
Zfish    78 RKSWPARLAQGDFPW----DDRDFRHLLLAASGVAALLLYLLFRDPGKEITWKDFV-----HRYL 133

  Fly   109 YKGNWIQVERTREQ-------QTLDLHMG-VPWETV-TLTAFGNNKGIYFDILEEAR-QLALEAT 163
            .:|...::|...:|       :..|.:.| ..|..: ::..|..|       ||.|. :|.||.:
Zfish   134 DRGLVERLEVVNKQFVRVILERDADANEGSYVWFNIGSVDTFERN-------LEAAHYELGLEPS 191

  Fly   164 EGKTVLYTA---------------------MGAEWRPFGHPRRRRPTGSVVLDRGTSQRI----- 202
            ....|:||:                     ......|.|.....|..|...:...|::.:
Zfish   192 HRAAVVYTSESDGSFLMSFIPTLLLIGFLLFTLRRGPMGGGMGGRRGGLFGMSESTAKMMKDSIE 256

  Fly   203 -----IADCQD----------FIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSV 252
                 :|.|::          |:|:...|...|....:|.:|.||||.||:....|.|||.....
Zfish   257 VKFKDVAGCEEAKVEIMEFVNFLKNPQQYQDLGAKIPKGAVLSGPPGTGKTLLAKATAGEANVPF 321

  Fly   253 CLLNLSE-----RGLTDDRLNHLLNVAPEQS--IILLEDIDAAFVSR-----EATPQQKSAFDGL 305
            ..:|.||     .|:...|:..:..:|.:.:  |:.:::|||....|     ....:|::
Zfish   322 ITVNGSEFLEMFVGVGPARVRDMFALARKNAPCILFIDEIDAVGKKRGGGNFGGNSEQEN----- 381

  Fly   306 NRITFSGLLNCLDGVGSTEARIVFMTTNYIDRLDPALVRPGRIDLKEYIG 355
               |.:.||..:||..|:...:|...||..|.|||||:||||.|.:.|:|
Zfish   382 ---TLNQLLVEMDGFNSSTNVVVLAGTNRPDVLDPALMRPGRFDRQIYLG 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980	43/227 (19%)
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	50/183 (27%)
afg3l1	XP_005163264.1	FtsH_ext	100..191	CDD:284011	22/102 (22%)
		FtsH_fam	206..698	CDD:273520	57/231 (25%)
		AAA	298..428	CDD:278434	44/137 (32%)
		Peptidase_M41	514..696	CDD:279742
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810