DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4908 and bcs1l

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001016865.1	Gene:	bcs1l / 549619	XenbaseID:	XB-GENE-1015027	Length:	419	Species:	Xenopus tropicalis

Alignment Length:	415	Identity:	258/415 - (62%)
Similarity:	318/415 - (76%)	Gaps:	2/415 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTLPDLVAGLSSNPYFGAGFGLFGVGAAAAILRKGLQGGVILFRRHCMITLEVPCRDKSYQWLLK 65
            |...|.||.|..||||||||||.|||.|.|:.|||.|.|:|.||||.|||||||.:||||||||.
Frog     1 MPFADFVAALKDNPYFGAGFGLVGVGTALALARKGAQFGMIAFRRHYMITLEVPSKDKSYQWLLS 65

  Fly    66 WITIRGARKTQHLSVETNFVQNDNGTIKTSYDFIPSIGKHLFQYKGNWIQVERTREQQTLDLHMG 130
            ||: ..|:.||||||||:::|:::|.|.|.:||:||.|.|...||..||::||.||:|.:|||.|
Frog    66 WIS-HYAKNTQHLSVETSYLQHESGRISTKFDFVPSPGNHFIWYKSKWIRIERNREKQMIDLHTG 129

  Fly   131 VPWETVTLTAFGNNKGIYFDILEEARQLALEATEGKTVLYTAMGAEWRPFGHPRRRRPTGSVVLD 195
            .|||:||.||.|..:.|:|:||:|||:|||:...||||:|.|:|||||.||.||||||..||||:
Frog   130 TPWESVTFTALGTKRDIFFNILQEARELALKQQVGKTVMYNAVGAEWRQFGFPRRRRPLSSVVLE 194

  Fly   196 RGTSQRIIADCQDFIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSVCLLNLSER 260
            .|.|::|:.|.:.||.:..||:.|||||||||||||||||||||||||||||||||:||::||:.
Frog   195 EGVSEKIVQDVKGFIDNPKWYSDRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSICLMSLSDG 259

  Fly   261 GLTDDRLNHLLNVAPEQSIILLEDIDAAFVSREATPQQKSAFDGLNRITFSGLLNCLDGVGSTEA 325
            .|:||||||||:|||:||||||||:|||||||:.|.:..:|:.|:.|:|||||||.||||.||||
Frog   260 SLSDDRLNHLLSVAPQQSIILLEDVDAAFVSRDLTKENPTAYQGMGRLTFSGLLNALDGVASTEA 324

  Fly   326 RIVFMTTNYIDRLDPALVRPGRIDLKEYIGYCTQYQLEEMFKNFFASSDTTKAEEFGKRVNSFGR 390
            ||||||||:||||||||:||||:|:|:|:||||.:||.:||..|:......:||.|.....|...
Frog   325 RIVFMTTNHIDRLDPALIRPGRVDVKQYVGYCTHWQLSQMFLRFYPDQTAVEAEAFASAALSSSD 389

  Fly   391 SASPAQIQGFFMKHKLSSPQTVIDS 415
            ..|.||:||.||.|| :.|...|.:
Frog   390 KISAAQVQGHFMMHK-TDPDGAIQN 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980	101/168 (60%)
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	111/151 (74%)
bcs1l	NP_001016865.1	BCS1_N	24..191	CDD:214980	101/167 (60%)
bcs1l	NP_001016865.1	AAA	226..355	CDD:365803	98/128 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	219	1.000	Domainoid score	I2599
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3193
Inparanoid	1	1.050	541	1.000	Inparanoid score	I1150
OMA	1	1.010	-	-		QHG53752
OrthoDB	1	1.010	-	-		D365561at33208
OrthoFinder	1	1.000	-	-		FOG0005110
OrthoInspector	1	1.000	-	-		oto104884
Panther	1	1.100	-	-	LDO	PTHR23070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R132
SonicParanoid	1	1.000	-	-		X279
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110