DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4908 and bcs1l

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_957476.2	Gene:	bcs1l / 394157	ZFINID:	ZDB-GENE-040426-938	Length:	420	Species:	Danio rerio

Alignment Length:	420	Identity:	257/420 - (61%)
Similarity:	326/420 - (77%)	Gaps:	3/420 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTLPDLVAGLSSNPYFGAGFGLFGVGAAAAILRKGLQGGVILFRRHCMITLEVPCRDKSYQWLLK 65
            |||.|.:..|..||||||||||.|||.|.|:.|||.|.|:|.||||.|||||||.:||||.|||.
Zfish     1 MTLSDFIGALKDNPYFGAGFGLVGVGTALAVARKGAQVGMIFFRRHYMITLEVPSKDKSYHWLLS 65

  Fly    66 WITIRGARKTQHLSVETNFVQNDNGTIKTSYDFIPSIGKHLFQYKGNWIQVERTREQQTLDLHMG 130
            ||| :.|:.||||||||:::|:::|.:.|.:||.||.|.|:..|...||:|||.||:|.:|||.|
Zfish    66 WIT-KHAKHTQHLSVETSYMQHESGKVHTQFDFHPSPGNHIIWYGRKWIRVERVREKQMMDLHTG 129

  Fly   131 VPWETVTLTAFGNNKGIYFDILEEARQLALEATEGKTVLYTAMGAEWRPFGHPRRRRPTGSVVLD 195
            .|||:||.||.|.::..:|:||:|||:|||:..||:||:||||||||||||.||||||..||||:
Zfish   130 TPWESVTFTALGRDRQTFFNILQEARELALKQEEGRTVMYTAMGAEWRPFGFPRRRRPLSSVVLE 194

  Fly   196 RGTSQRIIADCQDFIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSVCLLNLSER 260
            .|.::||:.|.::||.:..|||.||||||||||||||||||||||||||||||.||:||::||:|
Zfish   195 SGVAERIVDDVKEFIGNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITALAGELGYSICLMSLSDR 259

  Fly   261 GLTDDRLNHLLNVAPEQSIILLEDIDAAFVSREATPQQKS-AFDGLNRITFSGLLNCLDGVGSTE 324
            .|:||||||||:|||:||||||||:||||||||..|.:.. |:.|:.|:|||||||.||||.|:|
Zfish   260 SLSDDRLNHLLSVAPQQSIILLEDVDAAFVSRELLPTENPLAYQGMGRLTFSGLLNALDGVASSE 324

  Fly   325 ARIVFMTTNYIDRLDPALVRPGRIDLKEYIGYCTQYQLEEMFKNFFASSDTTKAEEFGKRVNSFG 389
            |||||||||:|:|||||||||||:|||:|:|:|:.:||.:||:.|:......:|:.|.::..:..
Zfish   325 ARIVFMTTNFIERLDPALVRPGRVDLKQYVGHCSHWQLTQMFRRFYPQESAAEADHFSEQALAAH 389

  Fly   390 RSASPAQIQGFFMKHKLSSPQTVIDSCEDI 419
            ...|.||:||.||.:| :.|...|.:..:|
Zfish   390 TDLSAAQVQGHFMLYK-TDPAGAIKNIAEI 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980	102/168 (61%)
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	113/152 (74%)
bcs1l	NP_957476.2	BCS1_N	24..176	CDD:214980	90/152 (59%)
		AAA	223..355	CDD:214640	102/131 (78%)
		AAA	226..355	CDD:278434	99/128 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590300
Domainoid	1	1.000	221	1.000	Domainoid score	I2548
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3193
Inparanoid	1	1.050	537	1.000	Inparanoid score	I1157
OMA	1	1.010	-	-		QHG53752
OrthoDB	1	1.010	-	-		D365561at33208
OrthoFinder	1	1.000	-	-		FOG0005110
OrthoInspector	1	1.000	-	-		oto40057
orthoMCL	1	0.900	-	-		OOG6_101424
Panther	1	1.100	-	-	LDO	PTHR23070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R132
SonicParanoid	1	1.000	-	-		X279
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800