DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4908 and bcs-1

DIOPT Version :9

Sequence 1:	NP_609358.1	Gene:	CG4908 / 34360	FlyBaseID:	FBgn0032195	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001022191.1	Gene:	bcs-1 / 174372	WormBaseID:	WBGene00010042	Length:	442	Species:	Caenorhabditis elegans

Alignment Length:	421	Identity:	203/421 - (48%)
Similarity:	274/421 - (65%)	Gaps:	3/421 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DLVAGLSSNPYFGAGFGLFGVGAAAAILRKGLQGGVILFRRHCMITLEVPCRDKSYQWLLKWITI 69
            ||...|:.||||.||.||.|:|.|.:.||:..|.....|||..||.|::...|.:|.|||.:|..
Worm    23 DLYDNLNQNPYFNAGAGLAGIGIAMSFLRRTAQISNTYFRRRFMINLQINNEDAAYPWLLDFINN 87

  Fly    70 RGARKTQHLSVETNFVQNDNGTIKTSYDFIPSIGKHLFQYKGNWIQVERTREQQTLDLH-MGVPW 133
            |.|.:|::||..|...|.::|..:.|..|:|..|.|.|.:...||:|||.||:|.:... :..|:
Worm    88 RSATQTRNLSANTVVHQAESGKTELSISFLPGHGTHFFVHDYRWIKVERQREKQVIQRDGIRTPF 152

  Fly   134 ETVTLTAFGNNKGIYFDILEEARQLALEATEGKTVLYTAMGAEWRPFGHPRRRRPTGSVVLDRGT 198
            ||||||..|::...:..:||::.:.|::..|...|:|.|:|.:|..||.||::|...||:||...
Worm   153 ETVTLTTLGSDVKFFKRMLEQSAKEAIDNAETGLVIYQAVGPQWIRFGVPRKKRDIESVILDGRI 217

  Fly   199 SQRIIADCQDFIKSSLWYTQRGIPYRRGYLLYGPPGCGKSSFITALAGELEYSVCLLNLSERGLT 263
            .:.::.|.|:||.|:.||..||:|||||||.|||||.||||||:|||....||||||:||||.|.
Worm   218 CEELVEDFQEFISSATWYADRGVPYRRGYLFYGPPGTGKSSFISALASHFGYSVCLLSLSERTLD 282

  Fly   264 DDRLNHLLNVAPEQSIILLEDIDAAFVSREATPQQKSAFDGLNRITFSGLLNCLDGVGSTEARIV 328
            |||||||||.||..|:::||||||||||||.......|:.||:|:|||||||.||||...|.|:.
Worm   283 DDRLNHLLNTAPPNSVVILEDIDAAFVSREDPMSNHPAYQGLSRVTFSGLLNALDGVACAEERLT 347

  Fly   329 FMTTNYIDRLDPALVRPGRIDLKEYIGYCTQYQLEEMFKNFFAS-SDTTKAEEFGKRVNSFGRSA 392
            ||||||::||||||:||||:|.|:|.|..|...|.:||..|:.. ||:..|:||.|||:......
Worm   348 FMTTNYVERLDPALIRPGRVDRKQYFGNATDGMLSKMFSRFYRQPSDSVLADEFVKRVSEHKTEL 412

  Fly   393 SPAQIQGFFMKHKLSSPQTVIDSCEDIWENV 423
            |||.|||.|:.:| ..|:..:|:.:::::.|
Worm   413 SPAMIQGHFLMYK-QDPRAALDNIKNMFKTV 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4908	NP_609358.1	BCS1_N	23..192	CDD:214980	62/169 (37%)
CG4908	NP_609358.1	RecA-like_BCS1	202..354	CDD:410918	100/151 (66%)
bcs-1	NP_001022191.1	BCS1_N	42..211	CDD:214980	62/168 (37%)
		AAA	243..377	CDD:214640	91/133 (68%)
		AAA	246..374	CDD:278434	87/127 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163841
Domainoid	1	1.000	183	1.000	Domainoid score	I2047
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3193
Inparanoid	1	1.050	396	1.000	Inparanoid score	I1115
Isobase	1	0.950	-	0	Normalized mean entropy	S476
OMA	1	1.010	-	-		QHG53752
OrthoDB	1	1.010	-	-		D365561at33208
OrthoFinder	1	1.000	-	-		FOG0005110
OrthoInspector	1	1.000	-	-		oto18239
orthoMCL	1	0.900	-	-		OOG6_101424
Panther	1	1.100	-	-	LDO	PTHR23070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R132
SonicParanoid	1	1.000	-	-		X279
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890