Protein Alignment Prosalpha6 and PSMA1

DIOPT Version :10

• Sequence 1: NP_523532.1
• Gene: Prosalpha6 / 34359
• FlyBaseID: FBgn0250843
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_683877.1
• Gene: PSMA1 / 5682
• HGNCID: 9530
• Length: 269
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 142/275 - (51%)
• Similarity: 201/275 - (73%)
• Gaps: 23/275 - (8%)

  Fly     2 FRNQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSDTQRKIIPI 66
            ||||||:||||||||||:||:||||||||.|:||||||:|.:||||||.:..|||:..|:||:.:
Human     8 FRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILHV 72

  Fly    67 DDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRYDRRPYGVG 131
            |:|:||||||||||||:|..::|.|||:.:..:|...|||||::.:|:|.|..||||.|||||||
Human    73 DNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVG 137

  Fly   132 LLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSSKDEIIRHGIRAIL 196
            ||:||||:.||||:|..|||.:|:|:|.|||:||||||||||:::::|::.:.:|:::||:||:.
Human   138 LLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALR 202

  Fly   197 GTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVAIAKENDNDTPRNDDDDDRP----- 256
            .|||.::   |....::::.|||||..|||.             ::|:.:|..:..::||
Human   203 ETLPAEQ---DLTTKNVSIGIVGKDLEFTIY-------------DDDDVSPFLEGLEERPQRKAQ 251

  Fly   257 --SPPEEPAAGPRDP 269
              .|.:|||....:|
Human   252 PAQPADEPAEKADEP 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6	NP_523532.1	proteasome_alpha_type_1	6..219	CDD:239718	122/212 (58%)
PSMA1	NP_683877.1	proteasome_alpha_type_1	12..222	CDD:239718	122/212 (58%)