DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha6 and Psma1

DIOPT Version :9

Sequence 1:	NP_001285798.1	Gene:	Prosalpha6 / 34359	FlyBaseID:	FBgn0250843	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_058974.1	Gene:	Psma1 / 29668	RGDID:	61841	Length:	263	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	141/269 - (52%)
Similarity:	199/269 - (73%)	Gaps:	16/269 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFRNQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSDTQRKIIP 65
            |||||||:||||||||||:||:||||||||.|:||||||:|.:||||||.:..|||:..|:||:.
  Rat     1 MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILH 65

  Fly    66 IDDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRYDRRPYGV 130
            :|:|:||||||||||||:|..::|.|||:.:..:|...|||||::.:|:|.|..||||.||||||
  Rat    66 VDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGV 130

  Fly   131 GLLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSSKDEIIRHGIRAI 195
            |||:||||:.|||::|..|||.:|:|:|.|||:||||||||||:::::|:..:.||:::||:||:
  Rat   131 GLLIAGYDDMGPHVFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMQCNLDELVKHGLRAL 195

  Fly   196 LGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVAIAKENDNDTPRNDDDDDRPSPPE 260
            ..|||.::   |....::::.|||||..|||.             ::|:.:|..|..::||....
  Rat   196 RETLPAEQ---DLTTKNVSIGIVGKDLEFTIY-------------DDDDVSPFLDGLEERPQRKA 244

  Fly   261 EPAAGPRDP 269
            :|:....:|
  Rat   245 QPSQAADEP 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6	NP_001285798.1	PRE1	4..231	CDD:223711	131/226 (58%)
Prosalpha6	NP_001285798.1	proteasome_alpha_type_1	6..219	CDD:239718	122/212 (58%)
Psma1	NP_058974.1	proteasome_alpha_type_1	6..216	CDD:239718	122/212 (58%)
Psma1	NP_058974.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	232..263		5/22 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338839
Domainoid	1	1.000	217	1.000	Domainoid score	I2597
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2712
OMA	1	1.010	-	-		QHG53705
OrthoDB	1	1.010	-	-		D1222564at2759
OrthoFinder	1	1.000	-	-		FOG0003679
OrthoInspector	1	1.000	-	-		otm45795
orthoMCL	1	0.900	-	-		OOG6_102143
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2552
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770