DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha6 and SPAC6G10.04c

DIOPT Version :9

Sequence 1:	NP_001285798.1	Gene:	Prosalpha6 / 34359	FlyBaseID:	FBgn0250843	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_594101.1	Gene:	SPAC6G10.04c / 2542559	PomBaseID:	SPAC6G10.04c	Length:	272	Species:	Schizosaccharomyces pombe

Alignment Length:	276	Identity:	129/276 - (46%)
Similarity:	174/276 - (63%)	Gaps:	19/276 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFRNQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSDTQRKIIP 65
            |||||||.|.|.|||||||||||||:||:|.|:|||||.:|.:||||||.:...|||..|:|:|.
pombe     1 MFRNQYDGDATTWSPQGRLHQVEYALEAIKQGSATVGLVSKTHAVLVALKRNAEELSSYQKKLIR 65

  Fly    66 IDDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRYDRRPYGV 130
            ||||:||:||||..||||||.|::.|.|:.|..:....||.||::.:..|.|..||.|.||||||
pombe    66 IDDHIGIAIAGLAPDARVLSNYMKQEALSSKTLFTRPIPVRRLMSKVAEKAQINTQEYGRRPYGV 130

  Fly   131 GLLVAGYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSSKDEIIRHGIRAI 195
            |.||.||||.|||:.:..||.........|:||||||||||:|:||:.|.|||::|:|...:||:
pombe   131 GFLVIGYDESGPHLLEFQPSGLVLEYLGTSMGSRSQSARTYIERNLDTFPDSSREELILSALRAL 195

  Fly   196 LGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVAIAKENDNDTPRNDD--DDDRPSP 258
            ..||..|:   :..:.:::::::|||:.:|:.              :.|||....|  .|..|:.
pombe   196 RDTLSKDQ---ELTEENVSISVIGKDEKYTLY--------------DQNDTKEWLDKLGDKGPAA 243

  Fly   259 PEEPAAGPRDPEVLVA 274
            .....|...:|:...|
pombe   244 ARASRAAAEEPQAPTA 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6	NP_001285798.1	PRE1	4..231	CDD:223711	117/226 (52%)
Prosalpha6	NP_001285798.1	proteasome_alpha_type_1	6..219	CDD:239718	111/212 (52%)
SPAC6G10.04c	NP_594101.1	PRE1	4..239	CDD:223711	121/251 (48%)
SPAC6G10.04c	NP_594101.1	proteasome_alpha_type_1	6..216	CDD:239718	111/212 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	181	1.000	Domainoid score	I799
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	247	1.000	Inparanoid score	I797
OMA	1	1.010	-	-		QHG53705
OrthoFinder	1	1.000	-	-		FOG0003679
OrthoInspector	1	1.000	-	-		otm47312
orthoMCL	1	0.900	-	-		OOG6_102143
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1003
SonicParanoid	1	1.000	-	-		X2552
TreeFam	1	0.960	-	-
	13	12.860