DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha6 and PSMA8

DIOPT Version :9

Sequence 1:NP_001285798.1 Gene:Prosalpha6 / 34359 FlyBaseID:FBgn0250843 Length:279 Species:Drosophila melanogaster
Sequence 2:NP_653263.2 Gene:PSMA8 / 143471 HGNCID:22985 Length:256 Species:Homo sapiens


Alignment Length:253 Identity:93/253 - (36%)
Similarity:142/253 - (56%) Gaps:23/253 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 NQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSD--TQRKIIPI 66
            ::||..:||:||.|.|.|||||.||||.|:..||::..:..||....|..::|.|  |.|||..:
Human     3 SRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKICAL 67

  Fly    67 DDHLGISIA------GLTADARVLSRYLRSECLNYKHSYD---TTYPVSRLITNLGNKMQTTTQR 122
            |||:.::.|      ||||||||:....|.||.::|.:.:   |...::|.|..|..|.   ||.
Human    68 DDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKY---TQS 129

  Fly   123 YDRRPYGVGLLVAGYDERG-PHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSSKDE 186
            ..|||:|:..|:.|:|:.| ..:||..||.|:...|||:||..:::.|.:||||..:...:|..|
Human   130 NGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSE 194

  Fly   187 IIRHGIRAILGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDSAKHVA-IAKEND 243
            .|:..|:|:|..:       .:|..:|.:||:.::||..:.|.|:...:|. |.||.:
Human   195 AIKLAIKALLEVV-------QSGGKNIELAIIRRNQPLKMFSAKEVELYVTEIEKEKE 245

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha6NP_001285798.1 PRE1 4..231 CDD:223711 88/238 (37%)
proteasome_alpha_type_1 6..219 CDD:239718 85/224 (38%)
PSMA8NP_653263.2 PRK03996 5..237 CDD:235192 89/241 (37%)
proteasome_alpha_type_7 5..219 CDD:239724 84/223 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1222564at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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