Protein Alignment Prosalpha6 and Prosalpha4

DIOPT Version :10

• Sequence 1: NP_523532.1
• Gene: Prosalpha6 / 34359
• FlyBaseID: FBgn0250843
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: XP_315431.3
• Gene: Prosalpha4 / 1276122
• VectorBaseID: AGAMI1_010744
• Length: 249
• Species: Anopheles gambiae
• Alignment Length: 246
• Identity: 83/246 - (33%)
• Similarity: 140/246 - (56%)
• Gaps: 13/246 - (5%)

  Fly     4 NQYDSDVTVWSPQGRLHQVEYAMEAVKLGTATVGLKNKDYAVLVALCKPTSELSD--TQRKIIPI 66
            ::||..:||:||.|.|.|||||.|||:.|:..:|::.||..||....|..::|.:  |.|||..:
Mosquito     3 SRYDRAITVFSPDGHLLQVEYAQEAVRKGSTAIGVRGKDVVVLGVEKKSVAKLQEERTVRKICLL 67

  Fly    67 DDHLGISIAGLTADARVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRYDRRPYGVG 131
            |.|:.::.||||||||||....:.:|.::|.|.:....:..:...:....|..||...|||:|:.
Mosquito    68 DHHVVMAFAGLTADARVLINRAQVQCQSHKLSEEDPVTLEYITRYIAELKQKHTQSNGRRPFGIS 132

  Fly   132 LLVAGYDERG-PHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSSKDEIIRHGIRAI 195
            .|:.|:|..| ||:|:..||..:...|||:.|..:::.|.:||::.:....|:::..|...|||:
Mosquito   133 CLIGGFDYDGVPHLYKTEPSGVYCEWKANATGRSAKTVREFLEEHYSPAAVSTEEGTITLAIRAL 197

  Fly   196 LGTLPTDEQGKDAGQYDITVAIVGKDQPFTIL---SNKDSAKHVAIAKEND 243
            |..:       .:||..:.||::.:|:|..:|   :.::..|.:.:|||.:
Mosquito   198 LEVV-------QSGQKSLEVAVMRRDEPMKMLDAQTIEEYVKKIELAKEEE 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha6	NP_523532.1	proteasome_alpha_type_1	6..219	CDD:239718	76/215 (35%)
Prosalpha4	XP_315431.3	proteasome_alpha_type_7	5..213	CDD:239724	76/214 (36%)