DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prosalpha6 and PSMB11

DIOPT Version :9

Sequence 1:NP_001285798.1 Gene:Prosalpha6 / 34359 FlyBaseID:FBgn0250843 Length:279 Species:Drosophila melanogaster
Sequence 2:NP_001093250.1 Gene:PSMB11 / 122706 HGNCID:31963 Length:300 Species:Homo sapiens


Alignment Length:289 Identity:63/289 - (21%)
Similarity:108/289 - (37%) Gaps:71/289 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 WS-PQGRLHQVEYAMEAVKL--GTATVGLKNKDYAVLVALCKPTSELSDTQR------------K 62
            |: |:|...|....:...:|  ||.|:..:.: :.|:.|        :||:.            |
Human    27 WAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFR-HGVIAA--------ADTRSSCGSYVACPASCK 82

  Fly    63 IIPIDDHLGISIAGLTADA----RVLSRYLRSECLNYKHSYDTTYPVSRLITNLGNKMQTTTQRY 123
            :||:..||..:.:|.:||.    |||.|.||...|. :....:....::|::.:.::.:      
Human    83 VIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELR-EGQLPSVASAAKLLSAMMSQYR------ 140

  Fly   124 DRRPYGVGLLVA----GYDERGPHIYQVTPSATFFNCKANSIGSRSQSARTYLEKNLNKFLDSSK 184
                 |:.|.||    |:|..||.::.|....|.......|:||.|..|...|::...  .|.|.
Human   141 -----GLDLCVATALCGWDRSGPELFYVYSDGTRLQGDIFSVGSGSPYAYGVLDRGYR--YDMST 198

  Fly   185 DE-------IIRHGIRAILGTLPTDEQGKDAGQYDITVAIVGKDQPFTILSNKDS-AKHVAIAKE 241
            .|       .:.|.         |.......|..|:...   ::..:..:|..|: ..:|.:.|.
Human   199 QEAYALARCAVAHA---------THRDAYSGGSVDLFHV---RESGWEHVSRSDACVLYVELQKL 251

  Fly   242 NDNDTPRNDDDDDRPSPPEEPAAGPRDPE 270
            .:   |..::|.....|  |||...|..|
Human   252 LE---PEPEEDASHAHP--EPATAHRAAE 275

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prosalpha6NP_001285798.1 PRE1 4..231 CDD:223711 52/247 (21%)
proteasome_alpha_type_1 6..219 CDD:239718 51/235 (22%)
PSMB11NP_001093250.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..23
proteasome_beta_type_5 50..237 CDD:239730 45/221 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 255..300 7/23 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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