| Sequence 1: | NP_001188769.1 | Gene: | Npc1a / 34358 | FlyBaseID: | FBgn0024320 | Length: | 1287 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_788277.1 | Gene: | SCAP / 35529 | FlyBaseID: | FBgn0033052 | Length: | 1276 | Species: | Drosophila melanogaster |
| Alignment Length: | 1076 | Identity: | 196/1076 - (18%) |
|---|---|---|---|
| Similarity: | 373/1076 - (34%) | Gaps: | 334/1076 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 341 FFTKWGTYFASNPGLTLIAGASLVVILGYGINFIEIT---TDPVKL------------WASPNSK 390
Fly 391 SRLERE----------------FFDTKFSP------------FYRLEQIIIKAVNLPQIVHNTSN 427
Fly 428 GPYTFGPVFDREFLTKVLDLQEGIKEINANGTQLKDICYAPLSDDGSEIDVSQCVVQSIWGYFGD 492
Fly 493 DRERLDDHD---EDNGFNVTY--LDALYDCISNPYLCLAPYGGPVDPAIALGGFLPPGDQLTGST 552
Fly 553 KFELANAIILTFLVKNHH-NKTDLENA-----------------LTWEKKFVEF-MTNYTKNNMS 598
Fly 599 QYMDIAFTSERSIEDELNRE---------SQSDVLTI-----------------LVSYLIMFMYI 637
Fly 638 AISLGHVKEFKRVFIDSKITLGIGGVIIVLASVVSSVGVFGYIGLPATLIIVEVIPFLVLAVGVD 702
Fly 703 NIFILVQTHQRDQRKPNETLEQ--QVGRILGKVGPSMLLTSLSESFCFFLGGLSDMPAVRAFALY 765
Fly 766 AGVALIIDFLLQITCFVSLFTLDTKRREEN-------RMDICCFIKGKKPDSITSNEGLLYKFFS 823
Fly 824 S--VYVPFLMKKIVRASVMVIFFAWLCFS--IAIAPRIDI---GLDQELAMPQDSFVLHYF---Q 878
Fly 879 SLNENLNIGPPVYFVLKGDLAYTNSSDQNLVCAGQYCNDDSVLTQIYLASRHSNQTYIA------ 937
Fly 938 --RPASSWIDDYFD-WAAAASSCCKYRKDSGDFCPHQDTSCLRCNITKNSLLRPEEKEFVKYLPF 999
Fly 1000 FLKDNPDDTCAKAGHAAYGGAVRYSNSHERLNIEAS--YFMAYHTILKSSADYFLALESA---RK 1059
Fly 1060 ISANITQMLQGRLMSNGV--------------PMASALTVEVFPYSVFYVFYEQYLTMWSDTLQS 1110
Fly 1111 MGISVLSIFVVTFVLMGFDVHSALVVVITITMIVVNLGGLMYYWNISLNAVSLVNLVMAVGISVE 1175
Fly 1176 FCSH------LVHSFA-----------------TSKSVSQIDRAADSLSKMGSSIFSGITLTKFA 1217
Fly 1218 GILVLAFAKSQIFQVFYFRMYLGIVVIGAAHGLIFL 1253 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Npc1a | NP_001188769.1 | NPC1_N | 31..274 | CDD:293023 | |
| 2A060601 | 33..1261 | CDD:273337 | 196/1076 (18%) | ||
| Sterol-sensing | 651..804 | CDD:289145 | 41/161 (25%) | ||
| SCAP | NP_788277.1 | Sterol-sensing | 390..542 | CDD:289145 | 40/160 (25%) |
| WD40 | <878..1227 | CDD:225201 | 19/102 (19%) | ||
| WD40 | 878..1185 | CDD:295369 | 19/102 (19%) | ||
| WD40 repeat | 887..942 | CDD:293791 | 10/64 (16%) | ||
| WD40 repeat | 945..983 | CDD:293791 | 6/25 (24%) | ||
| WD40 repeat | 989..1070 | CDD:293791 | |||
| WD40 repeat | 1079..1114 | CDD:293791 | |||
| WD40 repeat | 1120..1157 | CDD:293791 | |||
| WD40 repeat | 1162..1196 | CDD:293791 | |||
| WD40 repeat | 1201..1233 | CDD:293791 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C45460570 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1933 | |
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.830 | |||||